The influence of the interaction of fluoride (F) and aluminum (Al) on bioavailability in bacterial and mammalian systems

Fluoride and aluminum, which are known to form a strong complex, are both present in finished drinking water. The effect of F and Al on one another's tissue accumulation was determined using adult, male New-Zealand white rabbits. Fluoride accumulation in plasma, urine, incisors and tibia was increased as the F addition to the drinking water increased within groups receiving a single concentration of Al. In contrast, F accumulation in plasma, urine, incisors and tibia decreased as the Al concentration increased within groups receiving a single F concentration. In addition, Al levels of plasma and tibia were significantly increased by the addition of F to the drinking water, even in animals receiving no Al in their drinking water. Therefore, some of the toxicity associated with high F level might in fact be associated with Al or a combined form of F and Al.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Veterinary Biosciences

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Ahn, Hye-Won

Contributors dc:contributor

• Jeffery, Elizabeth H.

• Health Sciences, Toxicology
• Health Sciences, Public Health
• Environmental Sciences

Statement dc:rights

• Copyright 1994 Ahn, Hye-Won

Language dc:language

eng

Identifier

AAI9503125
(UMI)AAI9503125

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/20951