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University of Illinois at Urbana-Champaign
Fetal tissue containing the suprachiasmatic nucleus restores circadian rhythms in old rats
Abstract
dc:descriptionCircadian rhythms of body temperature, locomotor activity, and drinking in many rats deteriorate or even disappear with age. The suprachiasmatic nucleus (SCN) in the anteroventral hypothalamus has been identified as the major circadian pacemaker in mammals. When fetal tissue containing the SCN is transplanted into young rats whose circadian rhythms have been abolished by SCN lesions, the rhythms gradually reappear. The anatomical and electrophysiological properties of the SCN undergo changes with age. Such changes may underlie the deterioration of circadian rhythms of overt behaviors in aged animals.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Psychology
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2011
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Li, Hua
- Contributors dc:contributor
-
- Malpeli, Joseph G.
Subjects
dc:subject × 3Rights
dc:rights- Statement dc:rights
-
- Copyright 1996 Li, Hua
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
-
AAI9625156
(UMI)AAI9625156 - OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/20225