Lateral organization and dynamics of phospholipids in membrane

Studies of the lateral organization and dynamics of phospholipids were carried out using fluorescence techniques and enzymatic methods. Using resonance energy transfer, no specific interactions were observed between gramicidin and dansyl-labeled phosphatidylcholine, phosphatidylethanolamine, or phosphatidic acid. However, another integral membrane protein, D-β-hydroxybutyrate dehydrogenase (BDH), reorganized the phospholipids in the bilayer into a nonrandom distribution. Although the enzyme has a specific requirement for phosphatidylcholine for activity, the extent of energy transfer decreased in the order phosphatidic acid, phosphatidylcholine, phosphatidylethanolamine.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Biochemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Wang, Suke

Contributors dc:contributor

• Glaser, Michael

• Chemistry, Biochemistry

Statement dc:rights

• Copyright 1989 Wang, Suke

Language dc:language

eng

Identifier

AAI9011070
(UMI)AAI9011070

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/19460