Cell Type-specific Analysis of Human Interactome and Transcriptome

Cells are the fundamental building block of complex tissues in higher-order organisms. These cells take different forms and shapes to perform a broad range of functions. What makes a cell uniquely eligible to perform a task, however, is not well-understood; neither is the defining characteristic that groups similar cells together to constitute a cell type. Even for known cell types, underlying pathways that mediate cell type-specific functionality are not readily available. These functions, in turn, contribute to cell type-specific susceptibility in various disorders.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Computer Science

Year

2016

Author dc:creator

• Mohammadi, Shahin

Contributors dc:contributor

• Ananth Grama
• Wojciech Szpankowski
• David Gleich
• Jennifer Neville
• Markus Lill

• Cell type
• Interactome
• Tissue
• Transcriptome

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1371

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2587