Imprinted Magnetic Traps for Study on Particle Fluctuation, Ordering and Microfluidic Applications

Superparamagnetic particles embedded in a polymer matrix (bead) have been a corner-stone to numerous interdisciplinary studies and applications across a wide range of fields such as physics, chemistry, material science and biomedicine. Through designed magnetic field profiles, these polymeric magnetic beads have the potential to be activated to move along field gradients to realize targeted drug delivery, assembly of functional materials and marker-based cell isolation. During my pursuit of Ph.D. in Physics in Prof. R. Sooryakumar’s lab, I have worked on magnetic trapping platforms based on ferromagnetic thin-film patterns imprinted on a substrate. These design-based platforms serve as excellent candidates in functionalizing the aforementioned magnetic beads and open up a broad new scope of phenomena and applications to explore. This dissertation will summarize three major aspects of the versatile platform developed in our lab: (1) regulating Brownian fluctuations of submicron magnetic particles with monopole-like domain walls located on the vertex of a ferromagnetic zigzag wire, (2) assembly of magnetic microspheres into structures ranging from closely packed, branching chains to expanded within confinements provided by patterned time-orbiting magnetic potentials, and (3) on-chip magnetic cell separation and encapsulation into droplets for single-cell experiments.

Name thesis:degree_name

Doctor of Philosophy

Level thesis:degree_level

doctoral

Discipline thesis:degree_discipline

Physics

Grantor dc:publisher

The Ohio State University

Year dc:date

2013

Author dc:creator

• Chen, Aaron

Contributors dc:contributor

• Sooryakumar, R.

• Physics
• Condensed Matter Physics
• magnetic pattern
• thin-film
• trap
• Brownian fluctuation
• self-assembly
• microfluidic

Statement dc:rights

• unrestricted
• This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.

Language dc:language

English

Repository record dc:identifier

http://rave.ohiolink.edu/etdc/view?acc_num=osu1364490203

OAI identifier oai:identifier

oai:etd.ohiolink.edu:osu1364490203