Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1164 for “"microfluidic"”.
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Passive microfluidic interconnects
… procedures were developed to test two passive microfluidic interconnect rings held together by the friction forces on the contact surfaces. The second design forms fluid seals by means of thin flared rings of compliant material being compressed into undersized sockets. Interconnects were tested …
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Microfluidic gene synthesis
… availability of such technology. The use of microfluidic technology greatly reduces reaction volumes and corresponding reagent and handling costs. Additionally, microfluidic technology enables large numbers of complex reactions to be performed in parallel, while facilitating the automation …
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Microfluidic bubble logic
… soft robotics, printing and digital fabrication.Microfluidics, the art of handling nano-to pico-liter volume fluids, is leading to a revolution in large-scale automation of biology and analytical chemistry. However, current lab-on-chip technologies are dependent on external macro-scale control …
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Fabrication process for openable microfluidic devices and externally actuated microfluidic switch
… and external fast speed valves for actuation, a microfluidic switch for cell sorting capable of operating at 48 Hz was designed, fabricated and tested. The use of aluminum as a channel substrate provides channel strength and short heat dissipation times, and the use of aluminum oxide enhances …
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Microfluidic Electrical Impedance Spectroscopy
… of this study is to design and manufacture a microfluidic device capable of measuring changes in impedance valuesof microfluidic cell cultures. Tocharacterize this, an interdigitated array of electrodes was patterned over glass, where it was then bonded to a series of fluidic networks created …
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Microfluidic temporal cell stimulation
This thesis presents a novel microfluidic platform for investigating cellular signaling networks, combining a programmable system for generating arbitrarily complex temporal input stimulant concentration profiles with real-time fluorogenic monitoring of cell physiological response. While cellular …
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Microfluidic tools for metabolomics
… methods. The goal of this thesis is to develop microfluidics-based approaches for improving metabolic analysis of PI embryos and mammalian cells. This challenge necessitates two competencies: methods for automating chemical assays and methods for supporting cell cultures, which can be integrated …
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Rapid Prototyping Of Microfluidic Packages
In the area of MEMS there exists a tremendous need for communication between the micro-device and the macro world. A standard protocol or at least multiple standards would be of great use. Electrical connections have been standardized for many uses and configurations by the integrated circuit …
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Droplet behaviour in microfluidic devices
… a study to understand the various aspects of a microfluidic device. In the first half we take the role of an end user, experimenting to learn how best to use the device efficiently. In the second half we are the manufacturer, trying to fabricate a user friendly, and fully functioning …
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Microfluidic Electro-osmotic Flow Pumps
… multiplied, leading to an increased interest in microfluidics. Total integration of the detector and pump are necessary to decrease the overall size of the microfluidic device. Using previously developed thin film technologies, an electroosmotic flow (EOF) pump was incorporated in a microfluidic …
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Microfluidic Devices for Bioanalytical Applications
Poly(dimethylsiloxane) (PDMS) based microfluidic devices have a wide range of applications in chemistry, biology, environmental science and drug delivery. PDMS devices, fabricated using soft lithography were utilized in fabrication and optimization of biotin-avidin protein bioassay. In order to …
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Microfluidic device for cytotoxicity screening
… resource-intensive process. We have developed a microfluidic device with internal structures that can evenly distribute cells across five chambers and requires only microliter volume of cell culturing media. In this study, we performed fluid dynamic simulations of different microfluidic designs …
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Bioanalytical applications of microfluidic devices
… the thesis describes a new patterning technique--microfluidic contact printing--that combines several of the desirable aspects of microcontact printing and microfluidic patterning and addresses some of their important limitations through the integration of a track-etched polycarbonate (PCTE) …
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Silicon processing for microfluidic neuroprobes
… describes the fabrication process of a novel microfluidic-based neuroprobe capable of obtaining neuromodulators with high spatial and temporal resolution with limited tissue damage. This is achieved through the use of microfluidic channels with dimensions in the range of tens of microns, which …
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Microfluidic assembly of zein microcapsules
… process and the properties of the microcapsules. Microfluidics drew a great interest as a mean to synthesize or fabricate microcapsules. It features many advantages such as highly homogeneous and tunable product properties and non-invasive process, and makes handling of delicate materials …
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Microfluidic Methods for Biomolecular Analysis
Microfluidics is the science and technology of manipulating fluids at small scales ranging from microlitres (10$^{-6}$) to picolitres (10$^{-12}$). The fundamental physics is distinct from fluid behaviour on bulk scales and laminar flow is the key characteristic on this scale. Microfluidic systems …
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Microfluidic synthesis of colloidal nanomaterials
This thesis focuses on microfluidics based approaches for synthesis and surface-engineering of colloidal particles. Bottom-up assembly through colloidal nucleation and growth is a popular route to the controlled synthesis of nanomaterials. Standard bench-scale synthetic chemistry techniques often …
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Reversible concentric ring microfluidic interconnects
A reversible, Chip-to-Chip microfluidic interconnect was designed for use in high temperature, high pressure applications such as chemical microreactor systems. The interconnect uses two sets of concentric, interlocking rings with trapezoidal cross sections to form a fluid seal without the use of …
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Thermoplastic bonding of microfluidic substrates
The assembly of microfluidic components for lab on a chip (LOC) applications that are manufactured from commodity thermoplastics is challenging. A survey of plastic welding techniques validates that contour transmission laser welding is the most viable and commercially demonstrated option for …
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Integrated Disposable Microfluidic Tissue Chips
… conditions using multi-layer thermoplastic microfluidic chips with integrated elastomeric membranes. The new platform is designed for high-throughput experiments, using disposable thermoplastic chips, and enabling precise control of channel pressures and flowrates. The platform can …
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