Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΤΑΥΤΟΧΡΟΝΗΣ ΧΟΡΗΓΗΣΗΣ ΦΑΙΝΥΛΒΟΥΤΑΖΟΝΗΣ 'Η ΙΝΔΟΜΕΘΑΚΙΝΗΣ ΣΤΑ ΕΠΙΠΕΔΑ ΤΗΣ ΚΕΦΑΠΥΡΙΝΗΣ ΣΤΟΝ ΟΡΟ ΚΑΙ ΣΤΑ ΟΣΤΑ ΑΡΣΕΝΙΚΩΝ ΕΠΙΜΥΩΝ 2,5 ΚΑΙ 8 ΩΡΕΣ ΜΕΤΑ ΤΗΝ ΤΕΛΕΥΤΑΙΑ ΧΟΡΗΓΗΣΗ

THIS EXPERIMENTAL STUDY ON THE LEVELS OF CEPHAPIRIN IN THE SERUM AND THE BONES OF THE ANIMALS TESTED, WAS CARRIED OUT WITH OR WITHOUT THE SIMULTANEOUS ADMINISTRATION OF AN ANTI-INFLAMMATORY AGENT (PHENYLBUTAZONE OR INDOMETHACIN). THE FOLLOWING HAVE BEEN CONCLUDED: THE INCREASED LEVELS OF CEPHAPIRIN IN SERUM AND IN BOTH FEMORA, AFTER SIMULTANEOUS ADMINISTRATION OF PHENYLBUTAZONE, WERE STATISTICALLY SIGNIFICANT. MEASURABLE LEVELS OF CEPHAPIRIN IN THE HUMERUS, BUT PROPORTIONATELY LOWER THAN THE LEVELS OF EACH FEMUR, WERE FOUND ONLY AFTER SIMULTANEOUSADMINISTRATION OF PHENYLBUTAZONE. 5 HOURS AFTER THE LAST DOSE, CEPHAPIRIN CANNOT BE DETECTED IN THE BONES. NEITHER CAN IT BE DETECTED IN THE SERUM 8 HOURS AFTER THE LAST DOSE.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1988

Author dc:creator

• Μαρκέας, Νικόλαος

• ΑΛΛΗΛΕΠΙΔΡΑΣΕΙΣ ΦΑΡΜΑΚΩΝ
• ΕΠΙΠΕΔΑ ΣΤΑ ΟΣΤΑ
• Ινδομεθακίνη
• Κεφαπυρίνη
• Φαινυλβουταζόνη
• Cephapirin
• DRUG INTERACTIONS
• Indomethacin
• LEVELS IN BONES
• Phenylbutazone
• Ιατρική και Επιστήμες Υγείας
• Βασική Ιατρική
• Medical and Health Sciences
• Basic Medicine

Language dc:language

gre

Identifier

10.12681/eadd/1339

OAI identifier oai:identifier

oai:10442/1339