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Showing 1 to 13 of 13 for “"Phenylbutazone"”.
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The effects of phenylbutazone on a strain of fibroblasts cultivated in vitro
<p>Phenylbutazone was first synthesized in 1946 by H. Stenzyl during his investigation on pyrazole and pyrazoline derivatives. Although these compounds had been studied during the previous fifty years, the pharmacological properties were only recently recognized. It has been used clinically since …
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Physicochemical and tableting properties of crystallised and spray-dried phenylbutazone containing polymeric additives. Effect of polymeric additives (hydroxypropyl methylcellulose and a polyoxyethylene-polyoxypropylene glycol) on the crystalline structure, physicochemical properties and tableting behaviour of crystallised and spray-dried phenylbutazone powders
… properties of a poorly aqueous soluble drug, phenylbutazone, in alternative polymorphic form and containing low levels of two hydrophilic polymers - hydroxypropyl methylcellulose (H. P. M. C. ) and the surfactant poloxamer 188 - prepared by both conventional crystallisation and spray drying …
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Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΤΑΥΤΟΧΡΟΝΗΣ ΧΟΡΗΓΗΣΗΣ ΦΑΙΝΥΛΒΟΥΤΑΖΟΝΗΣ 'Η ΙΝΔΟΜΕΘΑΚΙΝΗΣ ΣΤΑ ΕΠΙΠΕΔΑ ΤΗΣ ΚΕΦΑΠΥΡΙΝΗΣ ΣΤΟΝ ΟΡΟ ΚΑΙ ΣΤΑ ΟΣΤΑ ΑΡΣΕΝΙΚΩΝ ΕΠΙΜΥΩΝ 2,5 ΚΑΙ 8 ΩΡΕΣ ΜΕΤΑ ΤΗΝ ΤΕΛΕΥΤΑΙΑ ΧΟΡΗΓΗΣΗ
… ADMINISTRATION OF AN ANTI-INFLAMMATORY AGENT (PHENYLBUTAZONE OR INDOMETHACIN). THE FOLLOWING HAVE BEEN CONCLUDED: THE INCREASED LEVELS OF CEPHAPIRIN IN SERUM AND IN BOTH FEMORA, AFTER SIMULTANEOUS ADMINISTRATION OF PHENYLBUTAZONE, WERE STATISTICALLY SIGNIFICANT. MEASURABLE LEVELS OF CEPHAPIRIN …
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ΠΕΙΡΑΜΑΤΙΚΗ ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΗΠΑΤΟΤΟΞΙΚΟΤΗΤΑΣ ΤΗΣ ΜΕΘΟΤΡΕΞΑΤΗΣ ΣΕ ΣΥΝΔΥΑΣΜΟ ΜΕ ΑΛΛΑ ΦΑΡΜΑΚΑ
… IS ENHANCED BY CONCOMITANT ADMINISTRATION OF PHENYLBUTAZONE OR PHENOBARBITAL, 2. PROBENECID ADMINISTRATION CAN PREVENT THE HEPATOTOXICITY CAUSED: A. BY THE COMBINATION OF "METHOTREXATE AND PHENYLBUTAZONE, B. BY THE COMBINATION OF "METHOTREXATE AND PHENOBARBITAL".
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Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΤΑΥΤΟΧΡΟΝΗΣ ΧΟΡΗΓΗΣΗΣ ΦΑΙΝΥΛΒΟΥΤΑΖΟΝΗΣ Η ΙΝΔΟΜΕΘΑΚΙΝΗΣ ΣΤΑ ΕΠΙΠΕΔΑ ΤΗΣ ΚΕΦΑΛΥΡΙΝΗΣ ΣΤΟΝ ΟΡΟ ΚΑΙ ΣΤΑ ΟΣΤΑ ΤΗΣ ΚΑΤΩ ΓΝΑΘΟΥ
… ADMINISTRATION OF TWO ANTI- INFLAMMATORY DRUGS (PHENYLBUTAZONE, INDOMETHACIN), ON THE LEVELS OF CEPHAPIRIN IN SERUM AND MANDIBLE WAS STUDIED IN RATS, TWO, FIVE AND EIGHT HOURS AFTER THE LAST SUBCUTANEOUS INJECTION. A HUNDRED AND EIGHT MALE WISTAR ALBINO RATS DIVIDED IN FIVE GROUPS WERE USED FOR …
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The Clinical Pharmacology of Acetaminophen in Adult Horses
… (COX) inhibitors, such as flunixin meglumine and phenylbutazone, which act through global inhibition of prostaglandin synthesis and release. While non-selective COX inhibitors are effective as anti-inflammatory agents, they are mired with complications with prolonged or high-dose use, particularly …
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Solid dispersions: formulation, characterisation, permeability and genomic evaluation
… phenacetin, indomethacin, chloramphenicol, phenylbutazone and succinylsulphathiazole. Solid dispersions were prepared using various drugs to polymer ratios. PEG 8000 was selected as a carrier in the solid dispersions. The study revealed that inclusion of drug within the polymeric matrix, …
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ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΗΣ ΠΕΡΙΕΚΤΙΚΟΤΗΤΑΣ ΣΕ ΚΑΛΛΙΚΡΕΙΝΗ ΤΟΥ ΟΛΙΚΟΥ ΣΙΑΛΟΥ ΤΟΥ ΑΝΘΡΩΠΟΥ IN VIVO ΚΑΙ ΤΩΝ ΥΠΟΓΝΑΘΙΩΝ ΑΔΕΝΩΝ ΤΩΝ ΕΠΙΜΥΩΝ IN VITRO ΜΕΤΑ ΤΗ ΧΟΡΗΓΗΣΗ ΑΝΤΙΦΛΕΓΜΟΝΩΔΩΝ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΟΥΣΙΩΝ.
… GLANDS OF 15 RATS AFTER THE ADMINISTRATION OF PHENYLBUTAZONE, DEXAMETHAZONE, INDOMETHACIN AND NIFLEUMIC ACID IN DIFFERENT MALARITIES. IN BOTH GROUPS THE RATES OF KALLIKREIN ARE CHARACTERIZED BY A QUICK DECREASE WHICH BEGINS IMMEDIATELY AFTER THE ADMINISTRATION OF THE ANTINFLAMMATORY AGENTS. IT …
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Studies on the stimulant action of human gamma-globulin on spontaneous contractility: interaction with K⁺-channel openers and postaglandin inhibitors
… Indomethacin, meclofenamic acid, corticosterone, phenylbutazone, aspirin, ibuprofen, and piroxicam all inhibited the stimulatory action of human gamma-globulin on the rat mesenteric portal vein, but only indomethacin, meclofenamic acid, and corticosterone did so to a significant level . …
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Rapid identification, confirmation, and quantitation using an open-air ion source coupled to a time-of-flight mass spectrometer
… three well known pharmaceuticals acetaminophen, phenylbutazone and clenbuterol. Further structural confirmation was explored through a determination of the number of active hydrogen atoms in an analyte molecule achieved by hydrogen/deuterium (H/D) exchange by treatment with deuterium oxide …
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The Interaction of Neisseria Gonorrhoeae with Human Monocytes
… whereas, incubation in iodoacetic acid and phenylbutazone inhibited phagocytic killing, probably as the result of impaired phagocytosis. These data indicate that freshly isolated and in vitro cultured adherent monocytes are capable of phagocytizing and killing N. gonorrhoeae, and that the …
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Evaluation of iohexol clearance to estimate glomerular filtration rate in normal horses
… of renal disease. Commonly used drugs such as phenylbutazone and gentamicin can be highly nephrotoxic under certain conditions. Estimation of the glomerular filtration rate (GFR), accepted as one of the earliest and most sensitive assessments of renal function, can be determined in horses using …
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Evaluation of Iohexol Clearance to Estimate Glomerular Filtration Rate in Normal Horse Foals
… of renal disease. Commonly used drugs such as phenylbutazone and gentamicin can be highly nephrotoxic under certain conditions. Of particular concern are those drugs, including the aminoglycoside antibiotics, that are eliminated almost exclusively by the kidney. Knowledge of a patients renal …