ΑΝΟΣΟΑΠΟΚΡΙΣΕΙΣ ΦΥΣΙΟΛΟΓΙΚΩΝ ΚΑΙ ΑΡΘΡΙΤΙΚΩΝ ΑΡΟΥΡΑΙΩΝ ΣΕ ΔΙΑΦΟΡΑ ΑΝΤΙΓΟΝΑ ΚΑΙ ΜΙΤΟΓΟΝΑ

IN OUR TRY TO STUDY THE MECHANISM BY WHICH EXPERIMENTAL ARTHRITIS (AID: ADJUVANT INDUCED DISEASE) INDUCED TO RATS WE STUDIED SOME IMMUNOLOGICAL PARAMETERS. INTHE BEGINNING WE FOUND THAT BACTERIAL LIPOPOLYSACCHARIDE FROM E.COLI IS A POLYCLONAL ACTIVATOR (MITOGEN) OF NORMAL RAT B-LYMPHOCYTES IN VIVO AND IN VITRO. INVITRO LPS ACTIVATES B-LYMPHOCYTES, ONLY AFTER ACTIVATION OF T-LYMPHOCYTES OR MACROPHAGES OR BOTH, WHICH IN TURN SECRETS FACTOR(S) WHICH HELP B-LYMPHOCYTES TORESPOND. THE MITOGENIC RESPONSES OF NORMAL OR AID RAT SPLENOCYTES TO LPS IS SIMILAR. IN CONTRAST THE MITOGENIC RESPONSE OF AID RAT SPLENOCYTES TO CON-A, 18-24 DAYS AFTER FREUD'S COMPLETE ADJUVANT (FCA) INJECTION (FOR AID INDUCTION) IS REDUCED COMPARED TO THE RESPONSE OF NORMAL RAT SPLENOCYTES. (SHORTENED)

Grantor dc:publisher

Aristotle University Of Thessaloniki (AUTH)

Year dc:date

1987

Authors dc:creator

• Yiangou, Minas
• Γιάγκου, Μηνάς

• ΑΝΟΣΟΑΠΟΚΡΙΣΕΙΣ
• ΚΥΤΤΑΡΑ ΠΟΥ ΣΧΗΜΑΤΙΖΟΥΝ ΑΝΟΣΟΠΛΑΚΕΣ
• ΜΙΤΟΓΟΝΙΚΕΣ ΑΠΟΚΡΙΣΕΙΣ
• ΠΑΡΑΓΩΓΗ ΛΕΜΦΟΚΙΝΩΝ
• Αρθρίτιδα, Πειραματική
• ADJUVANT INDUCE DISEASE AID
• Immune response
• LYMPHOKINE PRODUCTION
• MITOGENIC RESPONSES
• PLAQUE FORMING CELLS
• Φυσικές Επιστήμες
• Βιολογία
• Natural Sciences
• Biological Sciences

Language dc:language

gre

Identifier

10.12681/eadd/0664

OAI identifier oai:identifier

oai:10442/0664