ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΗΣ ΕΠΙΔΗΜΙΟΛΟΓΙΑΣ ΚΑΙ ΤΗΣ ΑΝΤΙΜΕΤΩΠΙΣΗΣ ΤΟΥ ΑΦΡΟΔΙΣΙΟΥ ΜΕΤΑΔΟΤΙΚΟΥ ΝΕΟΠΛΑΣΜΑΤΟΣ ΣΤΟ ΣΚΥΛΟ

IN THE PRESENT WORK ARE PRESENTED DATA ON THE INCIDENCE AND THE CLINICAL PICTURE OF TRANSMISSIBLE VENEREAL TUMOR (TVT) OF THE DOG, AS WELL AS THE RESULTS OF TREATING THE DISEASE BY MEANS OF CHEMOTHERAPY AND SURGERY. OF THE 6.660 DOGS ADMITTED TO THE CLINICS OF OBSTETRICS AND SURGERY OF THE FACULTY OF VETERINARY MEDICINE OF THE ARISTOTELIAN UNIVERSITY OF THESSALONIKI DURING THE 4- YEAR PERIOD OF 1982-1985, 554 WERE AFFLICTED WITH VARIOUS FORMS OF NEOPLASMS, OF WHICH 234 WERE DIAGNOSED AS TVT (3.5% OF THE TOTAL NUMBER OF DOGS). THE NEOPLASM APPEAREDWITH GREATER FREQUENCY AMONG FEMALE DOGS (P<0.001) AND AMONG DOGS OF LESS THAN5 YEARS OF AGE (P<0.001), LIVING IN THE OPEN AND REPRODUCING THEMSELVES WITHOUT CONTROL (MOSTLY GUARDIAN AND BEAGLE DOGS). THE NEOPLASM WAS LOCALIZED IN THE EXTERNAL GENITALIA OF ALL DOGS AND HAD ALREADY METASTASIZED IN 15 CASES. METASTASES WERE MORE FREQUENT AMONG MALE DOGS (P<0.001) AND HAD APPEARED AT THE EARLYSTAGES OF DEVELOPMENT OF THE TVT. THE GENERAL CONDITION OF THE ANIMALS WAS DISTURBED IN ONLY A FEW CASES. IN 40 DOGS TREATMENT CONSISTED OF THE ADMINISTRATION OF VINCRISTINE, CYCLOPHOSPHAMIDE AND METHOTREXATE, AND IN 140 DOGS OF VINCRISTINE ONLY. IN 18 CASES TREATMENT CONSISTED OF REMOVAL OF NEOPLASTIC TISSUES BY MEANS OF SURGERY. ALL THE ANIMALS OF THE FIRST GROUP WERE CURED; THERE WERE NO RELAPSES OF THE NEOPLASM IN THE ENSUING 2-YEAR PERIOD DURING WHICH THE ANIMALS WERE FOLLOWED UP. SURGICAL TREATMENT PROVED TO BE EFFECTIVE IN 64,3% OF THE CASES. ON COMPARISON OF SURGICAL TREATMENT WITH CHEMOTHERAPY, THE LATTER PROVED TOBE SIGNIFICANTLY MORE EFFECTIVE, SINCE IT CAN BE APPLIED IN PRACTICE MORE EASILY AND IT OFFERS MORE SEVERE CASES OF TVT. OF THE TWO CHEMOTHERAPEUTIC PROTOCOLS EMPLOYED, THE ONE CONSISTING OF VINCRISTINE ALONE WAS SHOWN TO BE MORE ADVANTAGEOUS, SINCE IT CAUSES FEWER SIDE-EFFECTS IN A LIMITED NUMBER OF ANIMALS, IT INVOLVES LOWER COSTS, AND IT IS JUST AS EFFECTIVE AS THE ONE CONSISTING OF VINCRISTINE, CYCLOPHOSPHAMIDE AND METHOTREXATE, WITHOUT INCREASING THE DURATION OF THE PERIOD OF TREATMENT.

Grantor dc:publisher

Aristotle University Of Thessaloniki (AUTH)

Year dc:date

1987

Author dc:creator

• Μπόσκος, Κωνσταντίνος

• ΑΦΡΟΔΙΣΙΟ ΜΕΤΑΔΟΤΙΚΟ ΝΕΟΠΛΑΣΜΑ
• Βινκριστίνη
• ΚΥΚΛΟΦΩΣΦΑΝΙΔΗ
• Μεθοτρεξάτη
• Νεοπλάσματα
• Σκύλοι
• Χημειοθεραπεία
• CANINE
• Chemotherapy
• Cyclophosphamide
• Methotrexate
• TRANSMISSIBLE VENEREAL TUMOR
• Tumours
• Vincristine
• Γεωπονικές Επιστήμες και Κτηνιατρική
• Κτηνιατρική
• Agricultural and Veterinary Sciences
• Veterinary Science

Language dc:language

gre

Identifier

10.12681/eadd/0540

OAI identifier oai:identifier

oai:10442/0540