Zinc enzyme model complexes with Ligands containing a N2S Donor Set and their methylating reactions

A new tridentate and two new tripodal ligands containing a N2S donor set have <br>been prepared in this work. These and other four selected ligands together with <br>different thiolate co-ligands have been used for the syntheses of 47 new zinc <br>enzyme model complexes. These complexes have been characterized and compared <br>by IR and NMR spectroscopy, 14 of them with single crystal structure analysis. <br>9 of the mononuclear tetrahedral N2S2 coordinated zinc complexes have been <br>investigated for the stepwise methylating reactions using the methylating <br>reagent iodmethane and trimethylphosphate. The result of the reactions indicates <br>that zinc-bound thiolates react with those methylating reagents. The methyl <br>group transfer occurs like in the enzymatic processes.

Author dc:creator

• Mian, Ji

Contributors dc:contributor

• Vahrenkamp, Heinrich

• Zink-Komplexe
• Enzyme-modell
• Methylierungen
• zinc complexes
• enzyme model
• methylations

Repository record source_url

https://freidok.uni-freiburg.de/data/1372

OAI identifier oai:identifier

oai:freidok.uni-freiburg.de:1372