Mitigation of the inflammatory response to bioprosthetic heart valve tissue through antigen-directed masking

This research was firstly directed to characterise the immune response to bioprosthetic heart valves in patients as well as in animal models. The study further demonstrated that the glutaraldehyde concentration applied to commercial heart valves is insufficient to mask the antigenicity of the tissue, therefore an method of masking antigens to mitigate the inflammatory response is needed.

Grantor dc:publisher.institution

Division of Cardiology

Year dc:date.issued

2009

Author dc:creator

• Du Plessis, Engela Helena

Advisor dc:contributor.advisor

• Human, Paul

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/2777

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/2777