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Aston University

Tetrahydrobiopterin metabolism

Abstract

dc:description.abstract

A technique for the measurement of biopterin using HPLC has been developed and compared against the established Crithidia fasciculata assay. The two assays give a similar reading when samples are unoxidised but after acid/iodine oxidation Crithidia reads higher, probably due to the presence of other pterins. Using HPLC as a measuring technique an oral dose of phenylalanine has been found to elevate the level of biopterin derivatives in the blood whilst tyrosine had no effect...

Degree

thesis:*
Name dc:type.qualificationname
Ph.D.
Level dc:type.qualificationlevel
doctoral
Grantor dc:publisher.institution
Aston University
Year dc:date.issued
1984

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Hamon, Christopher G.B.

Identifiers

dc:identifier.*
OAI identifier oai:identifier
oai:publications.aston.ac.uk:11757

Chain of custody

source
Harvested from
Aston University
Base URL
publications.aston.ac.uk/cgi/oai2
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
related terms
citation

Hamon, Christopher G.B.. Tetrahydrobiopterin metabolism. doctoral thesis, Aston University, 1984. https://doi.org/10.48780/publications.aston.ac.uk.00011757