Active Breathing Control (ABC) : Messung und Reduktion von ateminduzierten Organbewegungen des Thorax

PURPOSE: Extensive radiotherapy volumes for tumors of the chest are partly caused by interfractional organ motion. We evaluated the feasibility of respiratory observation tools using the active breathing control (ABC) system and the effect on breathing cycle regularity and reproducibility.METHODS AND MATERIALS: Thirty-six patients with unresectable tumors of the chest were selected for evaluation of the ABC system. Computed tomography scans were performed at various respiratory phases starting at the same couch position without patient movement. Threshold levels were set at minimum and maximum volume during normal breathing cycles and at a volume defined as shallow breathing, reflecting the sujective maximal tolerable reduction of breath volume. To evaluate the extend of organ movement, 13 landmarks were considered unsing commercial software for image coregistration. In 4 patients second examinations were performed during therapy.RESULTS: Investigating the differences in a normal breathing cycle versus shallow breathing, a statistically significant reduction of respiratory motion in the upper, middle an lower regions of the chest could be detected, representing potential movement reduction achieved through reduced breath volume. Evaluating interfraction reproducibility, the mean displacements ranged between 0.24 mm (chest wall/tracheal bifurcation) to 3.5 mm (diaphragm) for expiration and shallow breathing and 0.24 mm (chest wall) to 5.25 mm (diaphragm) for normal inspiration.CONCLUSION: By modifying regularity of the respiratory circle through reduction of breath volume a signigicant and reproducible reduction of the chest and diaphragm motion is possible, enabling reduction of treatment margins.

Grantor dc:publisher

Publikationsserver der RWTH Aachen University

Year dc:date

2009

Author dc:creator

• Kientopf, Aline

Contributors dc:contributor

• Eble, Michael J.

• info:eu-repo/classification/ddc/610
• Bronchialkrebs
• Bestrahlung
• Strahlentherapie
• Medizin
• Atemtriggerung
• Bestrahlungsgrenzen
• Planungszielvolumen
• Pneumonitis
• radiotherapy
• planning target volume

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

ger

Identifier

https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-113762%22

OAI record oai:identifier

https://publications.rwth-aachen.de/oai2d?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Apublications.rwth-aachen.de%3A51473