Gentamicinbeschichtung von Polyvinylidenfluorid-Netzmaterialien zur Infektionsprophylaxe bei Hernien-Reparationen

A gentamicin supplemetated PVDF mesh for hernia repair was constructed and analyse in vitro in regard of antibiotic effectiveness, gentamicin release and cytotoxicitiy. In vivo tests regarding biocampatibility (Ki67, CD68, TUNEL) were performed in an animal rat model. The gentamicin coating showed no negativ effect on Woundhealing and tissue regeneration. In contrast the coating induced a significantly increased collagen I/III ratio resulting in a stronger scar.

Grantor dc:publisher

Publikationsserver der RWTH Aachen University

Year dc:date

2008

Author dc:creator

• Preiß, Achim

Contributors dc:contributor

• Schumpelick, Volker

• info:eu-repo/classification/ddc/610
• Hernie
• Gentamicin
• Polyvinylidenfluorid
• Kollagen
• Medizin
• hernia
• PVDF
• collagen

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

ger

Identifier

https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112458%22

OAI record oai:identifier

https://publications.rwth-aachen.de/oai2d?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Apublications.rwth-aachen.de%3A49890