Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 271 for “"microarray analysis"”.
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Gene expression microarray analysis of small, purified cell subsets
Gene expression microarray technology is potentially capable of examining all of the cellular processes at the mRNA level at a given moment. One major challenge in its applicability is that most biological samples are cell mixtures and the cell type of interest is often a minor cell subset. Using …
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Spatiotemporal memories in honey bees: microarray analysis of time-trained foragers
… set that was inactive for each collection. Microarray analysis revealed that hundreds of genes were differentially expressed in the brain based on either time of day or activity state. A subset of these genes showed unique patterns of expression for each of the spatiotemporal foraging …
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Cross-species microarray analysis of limb development in the bat, Miniopterus natalensis
… or late development in female bats. A microarray analysis between the hand and foot plates of CS 16 and CS 17 bat embryos, and the hand plates of E 13.5 mouse embryos, revealed high correlation between the transcriptomes of the bat autopods and the mouse hand plate (r > 0.88) and among …
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cDNA microarray Analysis Identifies Symptom-Associated Chemokine Genes in Behcet's Disease Mouse Model
… blood mononuclear cells from each group, a cDNA microarray was performed. microarray chips were composed of 7,744 mouse genes. The BD skin group was compared with the BD eye group, and BD inactive group. The genes expressed differently and we selected genes of related to inflammation out of the …
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Construction of an ABF-1 inducible expression cell line utilized to conduct a microarray analysis
… induced ABF-1 expression and subjected to a microarray analysis. Early interpretations of the microarray data support the findings that ABF-1 may be regulating gene expression in a manner that facilitates withdrawal from the cell cycle.</p>
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A comparison of gene expression in tolerated and rejected islet grafts by gene microarray analysis
… expression studies. <br>Methods. Gene expression analysis in tolerated and rejected islet grafts was performed by using Affymetrix Murine U74A oligonucleotide arrays. Real-time PCR and RNase protection assay on selected genes were performed to confirm the results of microarray analysis. …
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Microarray Analysis of Soybean Treated With Fusarium Toxin and Development of a Soybean Gene Expression Database
… experiments, and to handle the large volumes of microarray expression data, an expression database equipped with analysis tools was constructed and a gene information database was developed to store and retrieve fundamental information on genes present on soybean cDNA microarray, such as Genbank …
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Microarray Analysis Identifies Novel Cholesterol Regulated Genes, Including Pcsk9 Which Regulates LDL Receptor Function and LDL Cholesterol Levels
… This thesis describes the identification by microarray technology of novel genes in cholesterol metabolism and the characterization of two of these genes. Microarray analysis of the livers of mice fed a low versus high cholesterol diet identified 37 down-regulated and 32 up-regulated genes. …
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Microarray analysis of Trichomonas vaginalis strains T1 and G3: Identifying genes that may contribute to virulence and metronidazole resistance
… In order to investigate these questions, a microarray analysis of two distinct strains of T. vaginalis , one being more virulent and slightly less metronidazole sensitive, was performed. This allowed the identification of several genes that may play a role in virulence and drug …
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A Genomic Assessment of Vicia Villosa Roth: Evaluation by Flow Cytometry, Canonical Discriminant Analysis, and Replicated cDNA Microarray Analysis
… spotted onto aminosilicated slides. The microarray data was analyzed using the individual fluorescence intensities to fit two statistical models with a mixed model analysis of variance using Proc Mixed in SAS. Ninety-seven of the 142 gene sequences (68%) were differentially expressed in …
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Identification of Anti-Beta2 Glycoprotein I Auto-antibody Regulated Gene Targets in the Primary Antiphospholipid Syndrome Using Gene Microarray Analysis
… expression and IL-8 production in vitro. Two microarray experiments tested differential global gene expression in 6 individual HUVEC donors in response to 5 different PAPS polyclonal anti-2GPI (50 mg/ml) compared to 5 normal control IgG (50 mg/ml) after 4 hours incubation . Total HUVEC RNA …
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SNAP Biclustering
… well in many problem domains, particularly DNA microarray analysis and collaborative filtering. A motivation for this work has been the biclustering technique known as bicACO, which was the first to use ant colony optimization. As bicACO is time intensive, much emphasis was placed on decreasing …
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An improved microarray image analysis architecture using mathematical morphology
DNA microarrays are now widely used to measure gene expression levels of healthy and cancerous cells. To allow further experiment for drug development to treat cancer, colour intensity from images of microarray spots need to be extracted as accurate as possible. The intensity extraction requires …
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Radioresistance in oral squamous cell carcinoma
… cell carcinoma. The methods of cell culture, microarray analysis and immunohistochemistry were employed to this end. Two novel radioresistant cell lines, PE-CAPJ41RR and PE-CAPJ49RR, were created and a number of targets identified using microarray analysis. Immunohistochemistry was used to …
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Regulation of ethylene receptor expression in Arabidopsis
… little effect upon expression of ETR1. Second, microarray analysis was performed using reciprocal mutants to examine ethylene-regulated gene expression. A large subset of ethylene-induced genes were involved in ethylene signal transduction. Among these, the ethylenereceptors ETR2, ERS1, and ERS2 …
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Gene expression profiling of myostatin null mice
… clenbuterol-induced skeletal muscle hypertrophy. Microarray analysis was not successful at identifying gene expression differences between clenbuterol-treated and control mice. Differences in gene expression between the MKO mice and wild type (WT) mice were observed including changes in genes …
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Intestinal Development and Gene Expression of Piglets Suckling Sows Transgenic for Human Insulin-Like Growth Factor-I
… at d 21 in the ileum of piglets suckling IGF. Microarray analysis elucidated differentially expressed genes involved in proliferation, as well as genes involved in immune function and metabolism, suggesting new avenues for IGF-I research.
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Investigations into the effects of berry flavonoids on nutrient transport processes in Caco-2 enterocytes
… To address this we carried out gene expression microarray analysis on intestinal Caco-2 cells treated with a flavonoid-rich berry extract (0.125 % w/v for 16 h). This microarray analysis identified alterations in numerous specific nutrient pathways, three of which were selected for further …
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Mcam/Muc18 Regulates Melanoma Progression By Modulating The Expression of Id-1
… cell lines, A375SM and C8161, and conducted cDNA microarray analysis. We identified and validated that the transcriptional regulator, Inhibitor of DNA Binding-1 (Id-1), previously shown to function as an oncogene in several malignancies, was downregulated by 5.6-fold following MUC18 silencing. …
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