Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 128 for “"bacterial pathogen"”.
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Exploring the Evolution of Pathogenicity in a Mult-host Bacterial Pathogen Using Comparative Genomics
Pantoea is a Gram-negative bacterial genus within the recently created Erwiniaceae. Pantoea members are found in association with a wide range of hosts, and some species have been reported as the causative agent of human infections. Despite this, little research has focused on the human …
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An obligate intracellular bacterial pathogen forms extensive and stable interkingdom contacts with the endoplasmic reticulum
Intracellular pathogens employ various mechanisms to manipulate host membranes, a critical strategy for subverting host pathways and advancing their life cycle. To this end, Rickettsia parkeri directly engages the host plasma membrane to infiltrate target cells and spread to neighboring ones. …
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The soil ecology of Serratia entomophila, A bacterial pathogen of the New Zealand grass grub, Costelytra zealandica (White)
… coloration before death. Insect pest control by pathogens is often not optimized because of insufficient knowledge of the pathogen's attributes. An understanding of the ecology of s. entomophila, in particular its persistence in the grass grub's environment, is essential if full advantage is to …
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DISSECTING THE ROLES OF DISTINCT DENDRITIC CELL SUBSETS IN THE IMMUNE RESPONSE TO THE INTRACELLULAR BACTERIAL PATHOGEN, LISTERIA MONOCYTOGENES
… the development of protective immunity to many pathogens and link the innate and adaptive immune systems. While DC as a whole have been studied extensively and are widely known for their ability to prime naïve T cells, there is much yet to be discovered about DC biology and function in responses …
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Ecology of the Brown Marmorated Stink Bug (Hemiptera: Pentitomidae): Oviposition on Different Trees, Nymphal Development on Various Vegetable Hosts, and Assessment of a Bacterial Pathogen
… red-sternum was associated with the potentially pathogenic red bacteria Serratia marcescens. Only one stink bug's gut contents had a confirmed infection of S. marcescens. Results from these studies offer insight into H. halys development on vegetable hosts and oviposition preferences on different …
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Data integration for the analysis of uncharacterized proteins in Mycobacterium tuberculosis
Mycobacterium tuberculosis is a bacterial pathogen that causes tuberculosis, a leading cause of human death worldwide from infectious diseases, especially in Africa. Despite enormous advances achieved in recent years in controlling the disease, tuberculosis remains a public health challenge. The …
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Uncovering Mechanisms of Cell Envelope Integrity and Nutrient Acquisition in Acinetobacter baumannii
Acinetobacter baumannii is an emerging bacterial pathogen of critical concern due to increasing multidrug resistance. The outer membrane (OM) of A. baumannii is a key barrier to antimicrobials and stressors but must also allow the entry of essential nutrients. The maintenance of lipid asymmetry …
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Innate Immunity to Listeria monocytogenes Infection: Regulation of Dendritic Cell and Neutrophil Responses by MyD88 and the Type I IFN Receptor
… monocytogenes (Lm)</italic> is an intracellular bacterial pathogen that is of consequence to pregnant women and immunocompromised individuals. Exploiting a niche, <italic>Lm</italic> gains access to the host cell cytosol via the pore forming toxin listeriolysin O (LLO) and infects a variety of …
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How Listeria monocytogenes crosses host cell barriers
Listeria monocytogenes is a bacterial pathogen that causes listeriosis, a severe food-borne illness that can cause severe complications and mortality in immunocompromised or pregnant people. Listeria is able to cross several host barriers to cause severe disease, including the intestinal barrier, …
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Multiple virulence genes and other MRNA regulatory targets are differentially expressed in two Helicobacter pylori strains overexpressing small RNAs
<p>Helicobacter pylori is a bacterial pathogen infecting the stomachs of half of humanity and the first bacterium listed as a carcinogen. Strains possessing the cytotoxin-associated gene pathogenicity island (cagPAI) are especially likely to cause symptomatic disease and cancer through the action …
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Evasion Of Innate Immunity By The Pathogen Coxiella Burnetii
… protect against microbial infections. In turn, pathogens have evolved ways to evade these strategies to remain undetected. The elegant interplay between these host-pathogen interactions is displayed by studies on the innate immune system, which is on a constant evolutionary arms race with …
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Intervention Strategies to Reduce Foodborne Pathogens in Poultry During Grow-out and Processing
Several foodborne pathogens like Salmonella spp., Campylobacter jejuni and Clostridium perfringens can occasionally be traced to poultry sources. The development of intervention strategies that are applicable to different stages of poultry production can help lessen the level of these pathogens in …
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TARGETING MULTI-DRUG RESISTANT PATHOGENS WITH NOVEL ANTIMICROBIAL PEPTIDES
… Half of these infections are attributed to the bacterial pathogen, methicillin resistant Staphylococcus aureus (MRSA) according to a report published in 2013 by the Centers for Disease Control and Prevention (CDC). Similarly, S. pseudintermedius is a leading cause of opportunistic infections in …
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Identification of the cir1 disease resistance gene in Arabidopsis thaliana
… and effectively respond to disease causing pathogens. The defence-related cir1 (constitutively induced resistance 1) mutant was first isolated in an effort to identify components of the Arabidopsis thaliana defence system essential for resistance against pathogens. The cir1 mutant has …
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Identification of Candidate Effector Proteins from Fusarium graminearum during Infection of Arabidopsis thaliana Using Proximity-Dependant Biotin Identification (BioID)
Fusarium graminearumis a fungal pathogen that causes Fusarium head blight (FHB) in cereal crops. Identifying proteins that are secreted from pathogens to overcome plant defenses and cause disease, collectively known as effectors, can reveal new targets for fungicides or other control …
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Cellular Dynamics and Disease Outcome of Type 3 Streptococcus pneumoniae Clinical Isolates Differ Between Strains
Streptococcus pneumoniae is a bacterial pathogen that continues to be a major cause of disease around the world. It is not only the number one cause of bacterial pneumonia but also the cause of about 15% of the deaths of children under 5 around the world. There is a lot of research done on this …
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Giant vesicles compressed by actin polymerization
… The discovery of actin based motility of the bacterial pathogen Listeria monocytogenes has lead to clearer understandings of the essential ingredients required for cell motility. The biophysical mechanisms by which these proteins generate forces is the subject of intense investigation. A novel …
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Development, characterization and transcriptional profiling of a mouse model of fatal infectious diarrhea and colitis
… rodentium is a naturally occurring murine bacterial pathogen which is used to model human diarrheagenic E. coli (EPEC and EHEC) infections in mice. C. rodentium causes colonic hyperplasia and a variable degree of colitis and mortality in the majority of inbred and outbred lines of mice. …
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Characterization of Redox Active Natural Compounds in Chlamydia Infection
… worldwide, induced by the intracellular bacterial pathogen Chlamydia trachomatis (Ct). Ct is also one of the most widespread sexually transmitted infections (STIs), with over 2.8 million infections in the US alone. The most serious sequelae result from ascension of Ct to the upper genital …
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