Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 196 for “"TCA"”.
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The Tca Cycle As A Nexus of Metabolic Vulnerabilities In Cancer
… metabolism (tricarboxylic acid cycle (TCA) and oxidative phosphorylation) is imperative for cancer cell growth and proliferation. The scope of the works presented in this dissertation is to explore the importance of mitochondrial metabolism, and primarily the TCA cycle—the anabolic …
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Energy metabolism in Arbidopsis thaliana: TCA cycle evolution, amino acids degradation and alternative pathways
… heritage is related to the tricarboxylic acid (TCA) cycle. The TCA cycle is an essential pathway which is related to reducing power (NADH and FADH2) generation, nitrogen assimilation and photosynthesis optimization. It has been suggested that the TCA cycle operated as isolated steps prior …
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Relações coordenadas entre ciclo TCA e ciclo celular em células específicas em resposta ao alumínio em Arabidopsis thaliana
… do ciclo dos ácidos tricarboxílicos (ciclo TCA). Ademais, agentes genotóxicos, incluindo o Al, induzem pausas no ciclo celular para que as células tenham tempo para reparar o DNA danificado e não transmiti-lo às células- filha. No entanto, pouco ou nada se sabe acerca de como o Al conecta o …
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The effect of beta-oxidation or TCA cycle inhibition on mitochondrial function and the sensitivity of high resolution respiratory detection
… metabolism do not account for defects in the TCA cycle and oxidative phosphorylation. These metabolic pathways are connected and dysfunction in one pathway (primary) could lead to dysfunction in the other (secondary). We propose the use of methods that combines all aspects of the bioenergetics …
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Predictive model to estimate ionized calcium from routine serum biochemical profiles in dogs
… calcium (piCa) to those of total calcium (tCa) and two corrected tCa formulae; and (3) study the relationship between biochemical values and variation of measured ionized calcium (miCa). This was a cross-sectional study. Records from 1,200 dogs who were patients at the University of …
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Análisis comparativo de los factores socioculturales y familiares en población universitaria y pacientes diagnosticados de trastornos de la alimentación
Los trastornos de la conducta alimentaria (TCA) son considerados un problema de salud pública por el aumento de su incidencia y por las graves alteraciones que producen. El desarrollo del trastorno alimentario es multicausal, ya que participan diversos factores biológicos, socioculturales, …
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Validation of an adjusted calcium formula using the Roche calcium (NMBATPA) and albumin (BCG) methods at Groote Schuur Hospital
… continue to adjust serum total calcium (tCa) concentration for serum albumin as a surrogate marker of calcium status, despite the availability of ionised calcium (iCa) measurement. Current recommendations by the Association for Clinical Biochemistry and Laboratory Medicine (ACB) advocate …
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An examination of critical issues in traditional Chinese acupuncture research
… in the field of Traditional Chinese Acupuncture (TCA), one of the treatment modalities of Traditional Chinese Medicine (TCM). TCM can be understood to constitute a distinct health care paradigm in the Kuhnian sense of having its own ontology, fundamental tenets, assumptions and practices. As TCA …
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Source identification of trichloroacetic acid with preparative capillary gas chromatography and accelerator mass spectrometry
… soil at ppb levels using trichloroacetic acid (TCA) as an exemplary compound was developed in the present thesis. A powerful approach to differentiate between biogenic and anthropogenic sources of environmental chemicals is to determine the radiocarbon content: an organic chemical derived from …
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Factores psicosociales en pacientes con diabetes mellitus tipo 1 y su implicación en el riesgo de desarrollar trastornos alimentarios.
… trastornos de la conducta alimentaria (TCA). La confluencia de ambas enfermedades conlleva altísimas tasas de morbimortalidad, por lo que se hace necesaria la detección precoz de estos trastornos en sujetos con DMT1. Sin embargo, existe escasa evidencia sobre la prevalencia de TCA y/o su …
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Investigation of Gut-Derived Circulating Succinate in Metabolism and Liver Signaling
<p>The tricarboxylic acid (TCA) cycle is the epicenter of cellular aerobic metabolism and accounts for the majority of cellular ATP production. In addition to its use in anabolic and catabolic processes, TCA cycle intermediates may serve as signaling molecules. The TCA cycle intermediates succinate …
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L’exercice et ses liens avec les troubles des conduites alimentaires chez l’athlète
… pour un trouble des conduites alimentaires (TCA), il est fréquent que l’exercice prenne une place importante et que le rapport à celui-ci devienne problématique dans le traitement et l’évolution de la maladie. Ce mémoire vise en premier lieu une meilleure compréhension de l’exercice compulsif …
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Cybersecurity Risk Assessment Matrix (CRAM): A System-Theoretic Approach to Balancing Operational and Cybersecurity Risk in the Management of Transient Cyber Assets (TCA) in the Maintenance of Operational Technology (OT)
… in this scenario as a Transient Cyber Asset (TCA). The introduction of a TCA to the FRCS/OT ecosystem is a well-known and significant threat vector. In this scenario, there are multiple actions that can be taken to mitigate the cybersecurity risk introduced by the TCA, but the solution is …
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Hepatocellular Carcinoma Image-Guided Intervention: Quantitative Characterization of Reagents For Thermochemical Ablation
<p>Thermochemical ablation (TCA) is a minimally invasive therapy under development for hepatocellular carcinoma, a leading cause of cancer death worldwide. TCA utilizes acid-base chemistry delivered simultaneously to induce local ablation when administered. When delivered via a mixing catheter …
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Relación entre los estilos de crianza y el desarrollo de los trastornos de la conducta alimentaria en adolescentes
Los trastornos de la conducta alimentaria (TCA) en adolescentes representan un problema creciente de salud pública, influenciado por factores biológicos, psicológicos y socioculturales. Entre estos, los estilos de crianza han sido identificados como un factor clave en la aparición y evolución de …
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Supply Chain Network Evolution: Demand-based Drivers of Interfirm Governance Evolution
… question in the transaction cost analysis (TCA) and relational exchange literatures. Some researchers purport that transactional governance provides superior performance by providing firms the flexibility to change suppliers. Others suggest that relational governance leads to superior …
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Evaluación de la función ejecutiva como factor pronóstico en pacientes con dependencia de alcoholque inician tratamiento ambulatorio.
… arterial. El trastorno por consumo de alcohol (TCA) se caracteriza por la pérdida de control en lo que a la ingesta de alcohol se refiere, lo que se relaciona con alteraciones en el funcionamiento de las estructuras cerebrales que regulan la motivación, el aprendizaje, la memoria, la atención y …
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Mathematical modelling of mammalian mitochondrial metabolism
… liver-specific tricarboxylic acid cycle (TCA) model developed within the Cell Systems Modelling Group (CSMG) was used to study and understand the basic functional properties of a tissue-specific TCA cycle model system and to form a knowledge base. Based on this knowledge, we successfully …
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