Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 446 for “"Optical microscopy"”.
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Ptychography for Nonlinear Optical Microscopy
In this thesis I will introduce a novel nonlinear optical microscopy method to address some of the shortcomings in the current nonlinear optical microscopy literature and offer a supplement to traditional fluorescent microscopy for label free optical biomedical imaging. In order to demonstrate this …
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Colocalization analysis for multimodal optical microscopy
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-08-01
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Methods for optical microscopy beyond conventional limits
Optical microscopy seeks to produce accurate and precise enlarged images of an object. It is highly desirable, particularly in live-cell biological microscopy, that the observation process does not perturb the structure, nor interfere with the dynamics, of the sample. These requirements are at odds …
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Near-field scanning optical microscopy with laser trapping
… of particle-trapped near-field scanning optical microscopy. This technique is unique in that it relies on the collection of scattered evanescent waves from a sample with a laser-trapped particle. In comparison with the other forms of near-field scanning optical microscopy with a tapered …
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Novel applications of advanced optical microscopy for microbiology
… of bacteria often requires visualisation by optical microscopy, but the use of advanced optical microscopy methods is uncommon by many microbiologists. Therefore, there remains many areas of microbiology which require exploration using newly developed techniques. This thesis describes the …
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Automatic 3D Neuron Tracing from Optical Microscopy Images.
… three-dimensional morphology of neurons from microscopy images. It is essential for delivering more comprehensive understanding of the relationship between neuronal structure and function, which is the fundamental to know how the brain works. However, currently neuron tracing remains a …
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Near Field Scanning Optical Microscopy (NSOM) of nano devices
This thesis aims to investigate the optical properties of nano-devices using the technique of Near-Field Scanning Optical Microscopy (NSOM). A unique setup to perform Atomic Force Microscopy (AFM) and NSOM simultaneously in a scanning electron microscope (SEM) to collect spatially resolved …
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Characterising nonlinear waveguides by scanning near-field optical microscopy
Scanning near-field optical microscopy (SNOM) has been applied to investigate the dispersion and nonlinear phenomena in a multimode Ta2O5 rectangular waveguide. Unlike the conventional approach of observing only the output spectra, the SNOM technique can collect the localised spectra from the …
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Scattering Scanning Near-Field Optical Microscopy on Anisotropic Dielectrics
Near-field optical microscopy allows the nondestructive examination of surfaces with a spatial resolution far below the diffraction limit of Abbe. In fact, the resolution of this kind of microscope is not at all dependent on the wavelength, but is typically in the range of 10 to 100 nanometers. On …
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Apertureless Scanning Nearfield Optical Microscopy with Ultra-high Temporal Resolution
By combining an apertureless scanning nearfield optical microscope (aSNOM) with a pump probe scheme, we create a novel experimental tool called pump probe apertureless scanning near field optical microscope (ppaSNOM), that combines a temporal resolution of 1ps with a spatial resolution of 20nm. …
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Advanced optical microscopy toolkits for non-invasive imaging in oncology
… such dynamics at the microscale, non-invasive optical toolkits offer the potential to identify, characterize, and visualize key molecules and their interactions in their native biological context, ranging from in vitro cell cultures to in vivo studies in both animal models and humans. In the …
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High throughput 3D optical microscopy : from image cytometry to endomicroscopy
Optical microscopy is an imaging technique that allows morphological mapping of intracellular structures with submicron resolution. More importantly, optical microscopy is a technique that can readily provide images with biochemical contrast based on different spectroscopic modalities such as …
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Investigation of optical near field using near field scanning optical microscopy
<p>Conventional optical imaging techniques have a fundamental resolution limit due to the diffraction limit of light. The advances of science and technology on the nanoscale demand a new tool for characterization. The Near Field Scanning Optical Microscopy (NSOM) has been developed to tackle …
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Model-based quantitative combinatorial optical microscopy for extracting clinical imaging biomarkers
… many noninvasive, high-resolution biomedical optical imaging techniques based on unique, yet complementary, contrast mechanisms have emerged. While each imaging modality is able to elucidate certain properties of the particular sample under study, an integrated approach in which all modalities …
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On-line laboratory for remote polymer crystallization experiments using optical microscopy
… thesis discusses the architecture of an on-line optical microscopy laboratory, or iLab, in which students remotely conduct and analyze polymer crystallization experiments using a polarized light microscope under controlled temperature conditions. The Polymer Crystallization iLab involves melting …
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Development of multiplexing strategies for electron and super-resolution optical microscopy/
… capabilities of electron and super resolution optical microscopy. This will be done through the development of molecular-scale barcodes that can be resolved in one of the two high resolution imaging modes. In the optical domain, the number of colors available in stochastic optical …
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Imaging and controlling atoms and semiconductor spins with advanced optical microscopy
… are implemented. In developing quantum systems, optical microscopy is central to controlling these quantum objects with their distinct atom-photon interactions, which enable quantum state preparation, manipulation, and detection with high spatial resolution. However, conventional capabilities of …
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Direct Measurements of Polyelectrolyte Brush Responses using Atomic Force and Optical Microscopy
… developed which combine force spectroscopy and optical microscopy. As well, established physico-chemical techniques are used. Polymer brushes provide an excellent building block for responsive surfaces. Surface properties that can be triggered are for example adhesion, charge, friction, …
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Label-free polarization-sensitive multimodal optical microscopy for collagen characterization in tissue
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01
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