Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 97 for “"Dermis"”.
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Improved Estimation of Transport Parameters in the Dermis
… DEET, diclofenac and parathion. Isolated human dermis obtained from surgical reduction was mounted in side-by-side diffusion cells in the presence and absence of a dialysis membrane (5000 MW cutoff) placed between the dermis and the donor solution. The results indicate that for permeants such as …
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Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI-COLUMBIA AT AUTHOR'S REQUEST.] Acellular tissue sources have become progressively popular for a variety of tissue engineering and medical applications, such as soft tissue augmentation, skin and vascular grafts, engineered scaffolds, and hernia …
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Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments
Second degree burns result in the destruction of the skin as well as its adnexa. Following such burns the wound heals without the formation of skin appendages and hair follicles. In normal embryonic development hair follicle formation requires the interaction between epithelial (keratinocytes) and …
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The control of melanogenesis in early avian embryos
… (Black Australorp x New Hampshire Red) chick epidermis and dermis have been used to demonstrate that premelanocytes migrate first through the sub-epidermal mesenchyme and then begin to cross into the epidermis from day 4. Results from these grafts and from tritium-labelling studies strongly …
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Histopathogenesis of eczma
… a mode of entry for the allergen into the epidermis and dermis, causing changes in both these structures, destructive in the epidermis and exudative in the dermis. Oedema fluid and lymphocytes from the upper dermis then force their way into the weakened epidermis to form vesicles. The degree …
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Die Rolle von cDermo-1 und cTwist im Vogelembryo
… function for cTwist in vivo. <br> <br>2) The dermis of the back develops from two separate progenitor populations of the dermomyotome differently regulated by signals from the surrounding structures. The dorsomedial population emanates from the medial lip, where it expresses Wnt-11 and …
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High frequency ultrasonic characterization of human skin In vivo
… to determine the characteristics of normal human dermis and subcutaneous fat. Attenuation coefficients were obtained by computing spectral slopes vs. depth, with the transducers axially translated to minimize diffraction effects. Backscatter coefficients were obtained by compensating recorded …
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Photorejuvenation Induced by 5-Aminolevulinic Acid Photodynamic Therapy in the Patients with Actinic Keratosis: A Histological Analysis
… of abnormal elastotic material in the dermis. Photodynamic therapy (PDT) is one of many treatment options available for photoaging; it has been shown to be effective, whereas the data on most other studies is based on clinical observation. Objectives: I investigated whether …
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Wundheilung von Vollhautdefekten durch Kombination einer autologen Keratinozyten-Fibrinkleber-Suspension (KFGS) mit einer dermalen Matrix mit und ohne Fibroblasten : ein Kurz- und Langzeitversuch am Schweinemodell
… x 5 cm) mit KFGS in Kombination mit azellulärer Dermis behandelt. Die Dermis wurde sowohl mit als auch ohne präkultivierte Fibroblasten transplantiert. Als Kontrollen dienten Wunden, die nur mit KFGS oder einer Fibroblasten-Keratinozyten-Fibrinkleber-Suspension transplantiert wurden. Der …
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Entwicklung eines Gewebeersatzes für postoperative Weichgewebedefekte
… Form einer humanen, sterilisierten azellulären Dermis sowie humaner dermaler Fibroblasten konnte ein komplexer Weichgewebsersatz geschaffen werden. Das Vorliegen typischer dermaler Strukturen, einer großen Durchlässigkeit für Modellsubstanzen, einer hohen Biokompatibilität sowie …
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Dual-Chambered Membrane Bioreactor for the Dynamic Co-Culture of Dermal Stratified Tissues
… as burning agents, and is composed of the epidermis, dermis, and hypodermis layers. When burned, skin cannot regulate temperature or fluid transport, or stop bacterial infection. Due to the importance of the skin barrier, natural healing and grafting treatments aim to quickly close the wounds …
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WNT SIGNALING AND HAIR FOLLICLE INITIATION
Dermis is required for structural integrity of the skin, and provides inductive cues for hair follicle initiation. Uniform Wnt signaling activity is present in dermal fibroblast precursors preceding hair follicle initiation, but the functional requirement of dermal Wnt signaling at early stages of …
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Notch Signaling Determines Lymphatic Cell Fate and Regulates Sprouting Lymphangiogenesis
… developing lymphatic vessels of the embryonic dermis and pathological lymphatic vessels of the wounded cornea. Dll4 was able to induce Notch activation in human dermal lymphatic endothelial cells (HDLECs), whereas Jagged1 (Jag1) was not. In HDLECs, Notch signaling is activated in response to …
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The role of fibrolast-derived cytokines on melasma
… normal sites, and solar elastosis at lesional dermis were significantly increased. The expression of HGF and SCF significantly increased at lesional dermis and the expression of c-kit was considerably increased at melanocytes of lesional epidermis. However, TNF-α was slightly decreased and …
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Dissecting adult epithelial cell plasticity using a model of oesophageal-to-skin lineage conversion
… mouse oesophageal epithelium to the mouse skin dermis, bearing empty niches for hair follicles. Whole-mount techniques together with immunofluorescence analysis revealed that oesophageal cells re-epithelialized the skin dermis and underlying niches, forming a new epithelium with associated …
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Experimental strategies for investigating passive and ultrasound-enhanced transdermal drug delivery
… delivery to the blood capillaries near the epidermis-dermis junction, it would be desirable to conduct in vitro US/SLS-enhanced transdermal diffusion experiments using split-thickness skin (STS) models, in which much of the dermis is removed in order to simulate the in vivo transdermal …
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Interspecies characterization and tissue engineering of the temporomandibular joint disc
… (3) enhancing protocols for chondrogenesis of dermis-derived cells. The first aim of this thesis characterized the biomechanical and biochemical properties of human TMJ disc in relation to several animal models. Significant regional and interspecies variations were indentified, though certain …
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Measurement of tissue optical properties during mechanical compression using swept source optical coherence tomography
… 1 minute were compared. Optical thickness of epidermis and light penetration depth in the dermis were measured. The extended Huygens-Fresnel model was applied to measure the scattering coefficient μs of skin specimens. μs of skin was measured to be about 10-17 mm-1 before compression and …
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Dendritic Cells in Normal and Inflamed Human Skin
… effector CD8+ T cells infiltrating the epidermis. Recent studies, however, show that inhibitors of tumor necrosis factor (TNF) are also effective therapeutics. Activated dendritic cells (DCs) produce large ammounts of TNF which acts in an autocrine loop to increase DC maturation. Thus, TNF …
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