Novel synthesis of 3,4-fused indoles

The goal of this project was to synthesize 3,4-fused indoles having a variety of ring sizes and a variety of functional groups. This has been accomplished by the development of a novel palladium-catalyzed route to 3,4-fused indoles. The key steps are two palladium-catalyzed reactions, an intramolecular Heck reaction followed by a reductive N-heteroannulation. Using this route, a number of 3,4-fused indoles were prepared in acceptable yields.

Name thesis:degree_name

MS

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Chemistry

Year dc:date.available

2001

Author dc:creator

• Hubbard, Jeremiah Wallace

Contributors dc:contributor

• Bjorn C. G. Soderberg.

• Organic chemistry

Identifier

https://researchrepository.wvu.edu/etd/1313

OAI identifier oai:identifier

oai:researchrepository.wvu.edu:etd-2316