Optical Resonators and Fiber Tapers as Transducers for Detection of Nanoparticles and Bio-Molecules

<p>In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.</p> <p>Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Electrical & Systems Engineering

Year dc:date.available

2014

Author dc:creator

• Yilmaz, Huzeyfe

Contributors dc:contributor

• Lan Yang
• Srikanth Singamaneni

• Microtoroid
• Fiber Taper
• Nanoparticle
• Peptide
• Thulium
• Raman Laser
• Biology and Biomimetic Materials
• Electromagnetics and Photonics
• Nanoscience and Nanotechnology
• Nanotechnology Fabrication
• Optics

Statement dc:rights

• I have not registered my thesis with the U.S. Copyright Office, but intend to later.

Language dc:language

English (en)

Identifier

https://openscholarship.wustl.edu/eng_etds/11

OAI identifier oai:identifier

oai:openscholarship.wustl.edu:eng_etds-1010