In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.
Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.
","abstract_html":"<p>In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.</p> <p>Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.</p>","abstract_has_math":false,"creators":["Yilmaz, Huzeyfe"],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Thesis","degree_discipline":"Electrical & Systems Engineering","degree_department":null,"school":null,"contributors":["Lan Yang","Srikanth Singamaneni"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2014,"date_issued":"2014-08-15T07:00:00Z","date_published":"2014-08-15T07:00:00Z","updated_at":"2026-07-24T06:13:31Z","subjects":["Microtoroid","Fiber Taper","Nanoparticle","Peptide","Thulium","Raman Laser","Biology and Biomimetic Materials","Electromagnetics and Photonics","Nanoscience and Nanotechnology","Nanotechnology Fabrication","Optics"],"languages":["English (en)"],"rights":["I have not registered my thesis with the U.S. Copyright Office, but intend to later."],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://openscholarship.wustl.edu/eng_etds/11"],"render_values":[{"text":"https://openscholarship.wustl.edu/eng_etds/11","href":"https://openscholarship.wustl.edu/eng_etds/11","code":true}]}]},"links":{"outbound_url":"https://doi.org/10.7936/K7RF5S0Z","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Lan Yang","Srikanth Singamaneni"]},{"key":"dc:creator","label":"Author","values":["Yilmaz, Huzeyfe"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2018-05-10T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical & Systems Engineering","McKelvey School of Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Microtoroid","Fiber Taper","Nanoparticle","Peptide","Thulium","Raman Laser","Biology and Biomimetic Materials","Electromagnetics and Photonics","Nanoscience and Nanotechnology","Nanotechnology Fabrication","Optics"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English (en)"]},{"key":"dc:rights","label":"Dc Rights","values":["I have not registered my thesis with the U.S. Copyright Office, but intend to later."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://doi.org/10.7936/K7RF5S0Z","https://openscholarship.wustl.edu/eng_etds/11"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Permanent URL: https://doi.org/10.7936/K7RF5S0Z"]},{"key":"dc:description.abstract","label":"Abstract","values":["In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.
Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.
"]},{"key":"dc:title","label":"Title","values":["Optical Resonators and Fiber Tapers as Transducers for Detection of Nanoparticles and Bio-Molecules"]}]}],"canonical_facts":{"dc:contributor":["Lan Yang","Srikanth Singamaneni"],"dc:creator":["Yilmaz, Huzeyfe"],"dc:date.available":["2018-05-10T07:00:00Z"],"dc:description":["Permanent URL: https://doi.org/10.7936/K7RF5S0Z"],"dc:description.abstract":["In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.
Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.
"],"dc:identifier":["https://doi.org/10.7936/K7RF5S0Z","https://openscholarship.wustl.edu/eng_etds/11"],"dc:language":["English (en)"],"dc:rights":["I have not registered my thesis with the U.S. Copyright Office, but intend to later."],"dc:subject":["Microtoroid","Fiber Taper","Nanoparticle","Peptide","Thulium","Raman Laser","Biology and Biomimetic Materials","Electromagnetics and Photonics","Nanoscience and Nanotechnology","Nanotechnology Fabrication","Optics"],"dc:title":["Optical Resonators and Fiber Tapers as Transducers for Detection of Nanoparticles and Bio-Molecules"],"thesis:degree_discipline":["Electrical & Systems Engineering","McKelvey School of Engineering"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T06:13:31Z"}