TARGETED POLYMER NANOPARTICLES FOR THE DETECTION AND TREATMENT OF DISSEMINATED COLORECTAL CANCER IN VIVO

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths and the fourth most common cancer in the United States. When CRC disseminates into the abdominal cavity, there can be hundreds, if not thousands, of small tumors infiltrating the surfaces of organs, making it extremely difficult to treat by conventional methods. Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in combination with cytoreductive surgery (CRS) has improved the 5-year survival rate of late-stage CRC patients from 12% to 51%. However, the survival rates of these patients have stagnated, which emphasizes the need for more innovative approaches to improve patient survival outcomes.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2018

Author dc:creator

• McCabe, Eleanor

• Colorectal Cancer

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/90738

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/90738