QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING

Bone fracture is a major complication of radiation therapy (RT). The etiology of RT-induced fractures is unclear, but likely involves bone damage and deterioration. Unfortunately, there remains a paucity of quantitative data on structural bone changes after exposure to RT. The primary goal of this project is to quantify RT-related structural bone changes in cancer patients using computed tomography (CT) scans obtained in the course of treatment. Our hypothesis is that exposure to radiation produces early structural changes in the cortical and trabecular bone compartments.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2017

Author dc:creator

• Okoukoni, Catherine

• Bone

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/82159

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/82159