Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 51 for “"Bone fracture"”.
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Bone fracture toughness of estrogen deficient rabbits
Bone mass is commonly used as an indicator of fracture risk. It has been shown in numerous studies that bone loss causes increased bone fragility and risk of fracture. It has also been shown that 50% of patients with osteoporotic vertebral compression fractures have the same bone mass as normal age …
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Regional and Seasonal Effects on Long Bone Fracture Characteristics
… skeletal trauma to determine the timing of bone fractures. Differentiating between perimortem trauma and postmortem damage is especially complicated due to the variable timing of bone degradation and subsequent changes in fracture morphology. Different investigations into the timing at which …
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Predictive modelling of the form and development of bone fracture healing
… of this study that the rate and formation of bone healing can be modelled mathematically and computationally, respectively, based on mechanical stimuli induced by the relative motion between bone fragments. To argue this case, the following hypotheses are tested; 1) the relationship between …
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Design and development of an adaptive external bone fracture fixation system
… a surgical treatment primarily utilised for long bone fracture stabilisation. External fixation, through either pin or wire insertion, is done by constraining bone fragments and providing support to the injury via external scaffolding built across the fracture., but it can also be used to solve …
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The Role of Gene Transcription and Inflammatory Cytokines in Bone Fracture Repair
… injury. However, in 5 to 10% of patients, fractures fail to properly heal resulting in non-union. A need exists for a more comprehensive understanding of the complex biology of fracture repair, which involves the coordinated work of many cell types including osteoblasts, osteoclasts, and …
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Diagnosing Bone Fracture to Assess Early Hominin Behaviour, Meat-Eating, and Socioecology at FLK-Zinjanthropus, Olduvai Gorge, Tanzania
… to diagnose hammerstone- and carnivore induced fracture. This is important because interpretations of hominin entry into the carnivore guild and evolution of meat-eating are based on rare tool and tooth marks in Oldowan (2.5-1.8mya) fossil assemblages. Consequently, estimating hominin and …
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Healing of Bone Fracture in Type 1 Diabetic Rat Models: a Potential Gene Therapy Using Bone Morphogenetic Protein
… related comorbidities, low-energy-trauma fracture is one of the major causes of morbidity and mortality of patients, due to the increased fracture risk in comparison with normal group and the impaired healing procedure after fracture. Bone morphogenetic proteins are well-known for their …
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Ultra-Wideband Imaging System For Medical Applications. Simulation models and Experimental Investigations for Early Breast Cancer & Bone Fracture Detection Using UWB Microwave Sensors
… analysis of cardiac tissues, soft tissues and bones. Microwave imaging uses non-ionizing ultra wideband (UWB) electromagnetic signals and utilises tissue-dependent dielectric contrast to reconstruct signals and images using radar-based or tomographic imaging techniques. Microwave imaging offers …
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Fracture characterization of cortical bone at the micrometer and nanometer length scales
Fracture in bone is common in a wide variety of health situations, and is of particular interest to structural engineers due to the adaptability of bone tissue in response to applied stresses. Investigations into the fracture processes within bone tissue can aid in developing medical therapies to …
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QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING
Bone fracture is a major complication of radiation therapy (RT). The etiology of RT-induced fractures is unclear, but likely involves bone damage and deterioration. Unfortunately, there remains a paucity of quantitative data on structural bone changes after exposure to RT. The primary goal of this …
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Production of temporary bone scaffold reinforced with OPEFB-CMC from oil palm empty fruit bunch
Bone fracture is a common injury because of its nature position that is mostly closest to skin and exposed to excessive compression and depression. Current treatment for bone fracture employs the scaffolding approaches which are specifically positioned for a certain period of time. These allow the …
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In vitro and in vivo assessments of PCL-TCP composites for bone tissue engineering
Currently, there is an unmet need for bone grafts which is the gold standard of treating patients with trauma related injuries or bone fracture. Autologous bone graft poses no issues of rejection but will result in donor site morbidity and is limited by defect size. Allografts and xenografts are …
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A dynamic supine stander for subjects with disabilities leading to prolonged immobility
Bone tissue needs to be exposed to loading in order to stimulate the osteogenic response of the body. Disabilities that lead to prolonged immobility will result in a decrease of the osteogenic processes and an increase in resorption of bone by osteoclast cells. This disuse modeling can lead to …
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Simulations of deformations and fracture of biological materials
We study deformations and fracture of soft and mineralized biological materials by using a finite element method. More specifically, we predict the deformation of a liver due to the pressure of a surgical tool. Secondly, we model the deformation of a cortical bone due to microindentation. Thirdly, …
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Impact of Hyperglycemia on Rat Cortical Bone Microstructure and Osteoprogenitor Cell Exhaustion
… has been associated with an increased risk of bone fracture and implant failure. However, the underlying reasons have yet to be entirely understood. Our group previously reported that osteocyte number appeared increased in the peri-implant bone of hyperglycemic rats, which might increase …
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MSC DERIVED EV IN REGENERATIVE MEDICINE
… patients suffering from osteoarthritis (OA) and bone fractures. Currently, there is no long-term therapy for OA; symptoms can be managed with anti-inflammatories and analgesics until they worsen to the extent that the damage becomes debilitating, and joint arthroplasty, is necessitated. However, …
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The Effect of Lycii Radicis Cortex Extract on Bone Formation in vitro and in vivo
… skeletal disease. It is caused by decreased bone mass and enhances the risk of bone fracture. In this study, I aimed to discover novel herbal extract(s) for the treatment of osteoporosis. I screened 64 ethanol extracts of edible plants native to Korea for their ability to increase the …
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Defining Novel Clusters of PPAR gamma Partial Agonists for Virtual Screening
… as weight gain, edema, and increased risk of bone fracture. Partial agonists could be an alternative to TZD-based drugs with fewer side effects. However, there is a lack of understanding of the types of PPARγ partial agonists and how they differ from full agonists. In silico techniques, like …
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Evaluation of Current Decision Rules and Healthcare Professional Practices for Detecting Osteoporosis Risk in the Young Adult Population
… factors. An individual’s risk for experiencing a bone fracture as a senior citizen increases without early intervention. Healthcare professionals do not have access to validated survey tools to identify young adults in need of osteoporosis prevention education, although survey tools to identify …
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Women's Actions Related to Health Behaviors after Receiving Bone Mineral Density Results: An Exploratory Study
Bone densitometry is the only clinically acceptable and objective method for the accurate measurement of bone mineral density (BMD), bone mass, and the prediction of bone fracture risk. Dual energy X-ray absorptiometry (DXA) is the primary diagnostic bone densitometry tool used in clinical …
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