Streptococcus pneumoniae mediated negative regulation of CD8+ T cell effector function

Infection with influenza A virus (IAV) can lead to increased susceptibility to subsequent bacterial infection, often with Streptococcus pneumoniae (Spn). Clinical and experimental data indicate increased disease severity when a coinfecting agent is present during IAV infection, indicating the need to understand how the presence of a coinfecting pathogen can modulate the ongoing adaptive CD8+ T cell response to IAV.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2016

Author dc:creator

• Blevins, Lance Kendall

• Coinfection

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/62646

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/62646