The Association of Celecoxib, Rofecoxib, and Non-selective NSAIDs with Indices of Thrombosis and Endothelial Function in the Multi-Ethnic Study of Atherosclerosis

Cyclooxygenase-2 (COX-2) inhibitors and non-selective nonsteroidal anti-inflammatory medications (NSAIDs) have been associated with increased cardiovascular risk. It is the intent of this discussion to explore mechanisms by which celecoxib, rofecoxib, and nonselective anti-inflammatory medications influence cardiovascular risk. Specifically, I will present data from the Multi-Ethnic Study of Atherosclerosis in order to identify an association of nonsteroidal anti-inflammatory medications with indices of thrombosis and endothelial function. It is my hope that this discussion will lead to a more complete understanding of the cardiovascular risk associated with this class of medications that has had a dramatic effect on public health.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2009

Author dc:creator

• Allen, Stewart

• COX-2 inhibitors

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/10339/14708

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/14708