Artificial and natural nucleic acid self assembling systems

<p>Nucleic acids are good candidates for nanomachine construction. They participate in all the processes of life, and so can function as structural building blocks and dynamic catalysts. However, to use nucleic acids as nanomachines, a better understanding of their material properties, how to design structures using them, and their dynamics is needed. We have tried to address these issues, in a small way, with nucleic acid force field development, an attempt at nanostructural design and synthesis using DNA, and a study of the RNA/protein regulatory dynamics of the tryptophan regulatory attenuation protein.</p>

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Open Access Dissertation

Discipline thesis:degree_discipline

Chemistry

Year dc:date.available

2011

Author dc:creator

• Wood, Marcus

Contributors dc:contributor

• John SantaLucia, Jr.
• David Rueda

• DNA
• force field
• nanotechnology
• RNA
• TRAP
• tryptophan regulation
• Biophysics
• Chemistry
• Nanoscience and Nanotechnology

Repository record dc:identifier

https://digitalcommons.wayne.edu/oa_dissertations/298

OAI identifier oai:identifier

oai:digitalcommons.wayne.edu:oa_dissertations-1297