Constituents of Ipomoea pes-caprae L. R. Br.

A study of the constituents of Ipomoea pescaprae L.R. Br. was made as a part of a systematic attempt to isolate anticancer compounds of natural origin. Initial extraction and fractionation of the plant material failed to yield any fractions with significant in vivo activity in the P-388 tumor system, and it was concluded that the plant is not a good source of active anti-cancer compounds. A study of the secondary metabolites of the plant revealed the presence of β-sitosterol and a complex mixture of glycolipids. Two components of the glycolipid mixture were characterized as β-rhamno-pyranosyl-11-hydroxyhexadecanoic acid and β-fucopyranosyl-11-hydroxyhexadecanoic acid. In addition, the plasticizer bis-(2-ethylhexyl)phthalate was identified as a contaminant of certain batches of chloroform used in this work.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Chemistry

Department dc:contributor.department

Chemistry

Grantor dc:publisher

Virginia Polytechnic Institute and State University

Year dc:date.issued

1976

Author dc:creator

• Simpers, Bruce Robert

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10919/53048

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/53048