{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/53048"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/53048","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Constituents of Ipomoea pes-caprae L. R. Br.","abstract":"A study of the constituents of Ipomoea pescaprae L.R. Br. was made as a part of a systematic attempt to isolate anticancer compounds of natural origin. Initial extraction and fractionation of the plant material failed to yield any fractions with significant in vivo activity in the P-388 tumor system, and it was concluded that the plant is not a good source of active anti-cancer compounds. A study of the secondary metabolites of the plant revealed the presence of β-sitosterol and a complex mixture of glycolipids. Two components of the glycolipid mixture were characterized as β-rhamno-pyranosyl-11-hydroxyhexadecanoic acid and β-fucopyranosyl-11-hydroxyhexadecanoic acid. In addition, the plasticizer bis-(2-ethylhexyl)phthalate was identified as a contaminant of certain batches of chloroform used in this work.","abstract_html":"A study of the constituents of Ipomoea pescaprae L.R. Br. was made as a part of a systematic attempt to isolate anticancer compounds of natural origin. Initial extraction and fractionation of the plant material failed to yield any fractions with significant in vivo activity in the P-388 tumor system, and it was concluded that the plant is not a good source of active anti-cancer compounds. A study of the secondary metabolites of the plant revealed the presence of β-sitosterol and a complex mixture of glycolipids. Two components of the glycolipid mixture were characterized as β-rhamno-pyranosyl-11-hydroxyhexadecanoic acid and β-fucopyranosyl-11-hydroxyhexadecanoic acid. In addition, the plasticizer bis-(2-ethylhexyl)phthalate was identified as a contaminant of certain batches of chloroform used in this work.","abstract_has_math":false,"creators":["Simpers, Bruce Robert"],"institution":"Virginia Polytechnic Institute and State University","degree_name":"Master of Science","degree_level":"masters","degree_discipline":"Chemistry","degree_department":"Chemistry","school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1976,"date_issued":"1976","date_published":"1976","updated_at":"2026-07-24T05:55:57Z","subjects":[],"languages":["en"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10919/53048","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.department","label":"Department","values":["Chemistry"]},{"key":"dc:creator","label":"Author","values":["Simpers, Bruce Robert"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2015-06-23T19:08:13Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2015-06-23T19:08:13Z"]},{"key":"dc:date.issued","label":"Date","values":["1976"]},{"key":"dc:publisher","label":"Institution","values":["Virginia Polytechnic Institute and State University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.dcmitype","label":"Dc Type Dcmitype","values":["Text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Virginia Polytechnic Institute and State University"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://rightsstatements.org/vocab/InC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10919/53048"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["A study of the constituents of Ipomoea pescaprae L.R. 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Initial extraction and fractionation of the plant material failed to yield any fractions with significant in vivo activity in the P-388 tumor system, and it was concluded that the plant is not a good source of active anti-cancer compounds. A study of the secondary metabolites of the plant revealed the presence of β-sitosterol and a complex mixture of glycolipids. Two components of the glycolipid mixture were characterized as β-rhamno-pyranosyl-11-hydroxyhexadecanoic acid and β-fucopyranosyl-11-hydroxyhexadecanoic acid. 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