The Safety and Adequacy of Galactooligosaccharides and Fructooligosaccharides in Infant Pig Formula

Breast milk remains the optimum vehicle to deliver high quality nutrients, including oligosaccharides, in quantities sufficient to sustain normal growth, however, it is currently unknown whether the addition of prebiotics to infant formula would alter neonate growth and development. The objective of this study was to determine the effect of Galactooligosaccharides (GOS) and Fructooligosaccharides (FOS) supplementation in nursery pig diets on growth and efficiency of food utilization. Forty-eight 4-day old crossbred pigs (1.628 ± .037 Kg BW) were randomly assigned to 1 of 8 diets: 1) milk-based formula containing Type 2 GOS and Type 1 FOS (4 + 1 g/L); 2) soy-based formula containing Type 1 FOS (3g/L); 3) milk-based formula with no prebiotic added; 4) milk-based formula containing Type 2 GOS only (5g/L); 5) milk-based formula containing Type 1 GOS only (5g/L); 6) milk-based formula containing Type 2 GOS and Type 2 FOS (4 + 1 g/L); 7) milk-based formula containing Type 1 GOS and Type 1 FOS (4 + 1 g/L); 8) soy-based formula with no prebiotic added. Diets were isonitrogenous, isocaloric and fed at 250 mL/kg body for a 2-week period. At sacrifice, blood and tissue samples were collected for analysis. A diet by time interaction (P < 0.001) indicated a smaller rate of accretion in bone mineral content for soy-based diets. Total bacteria and lactobacillus were significantly affected by treatment (P < 0.001). In conclusion, the addition of GOS and FOS to formula does not appear to alter growth however, the gut microbiota was significantly modified.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Animal and Poultry Sciences

Department dc:contributor.department

Animal and Poultry Sciences

Grantor dc:publisher

Virginia Tech

Year dc:date.issued

2014

Author dc:creator

• Brooks, Kayla Leanne

Chair dc:contributor.committeechair

• Rhoads, Robert P.

Committee members dc:contributor.committeemember

• El-Kadi, Samer Wassim
• Ponder, Monica A.

• oligosaccharides
• pigs
• growth
• microbiota

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Dc Identifier Other

vt_gsexam:3623

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/50440