Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 794 for “"microbiota"”.
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Host-Microbiota Interactions
… have helped delineate the important role of gut microbiota on human health. Changes in gut microbiota composition have consistently been observed in various health conditions, including colorectal cancer (CRC). Studies show that the microbiota fills in a variety of niche metabolic pathways that …
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The gut microbiota in depression
The accruing data linking the gut microbiota to the development and function of the central nervous system has been proposed as a paradigm shift in neuroscience. Neuroimmune, neuroendocrine and neural communication pathways exist between host and microbe. These pathways are components of the …
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Towards engineering the gut microbiota
… to the goal of rational engineering of the gut microbiota, these studies reveal ecological considerations that may promote or inhibit colonization by introduced commensals in this complex ecosystem. This work invites provides a conceptual framework for integrating systems microbial ecology with …
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Alterations in preconception, antenatal, and postnatal maternal gut microbiota influence offspring intestinal microbiota and immunity
Maternal microbiota during pregnancy, as well as maternal disease state, may impact offspring gut bacterial colonisation. Here, we explore the impact of maternal antibiotics during gestation and/or nursing on offspring gut microbiota. Further, we investigate the effect of preconception helminth …
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Examining the gut microbiota in aging
… metabolism, immunity, and behavior through the microbiota-gut-brain axis (MGBA). Key functions include fermenting complex carbohydrates into short-chain fatty acids (SCFAs) that maintain gut integrity, modulating inflammation, and influencing energy homeostasis (i.e., food intake regulation). …
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Antibiotic resistance in the gut microbiota
… the effects of antibiotics on the gut microbiota, as well as the potential for such populations to act as a reservoir for resistance genes, is imperative. This thesis set out to investigate the gut microbiota of antibiotic treated infants compared to untreated controls using …
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Cystic fibrosis and the gut microbiota
The role of the gut microbiota in host health has been established in recent years and has been shown to be altered in numerous disease states, including Cystic Fibrosis (CF) cohorts. This thesis investigates the gut microbiota and microbiome in CF persons and how it may be manipulated through …
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Mapping the microbiota in hidradenitis suppurativa
… HS. Our hypothesis is that gut, as well as skin, microbiota alterations and their metabolites, may be responsible for skin inflammation in HS. The level of pain experienced by 150 patients with HS was measured using the visual analogue scale and EQ-5D-5L questionnaires. 59 patients with HS …
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Comparative analysis of primate hydrogenotrophic microbiota
… that the host species-specific hydrogenotrophic microbiota can be observed in some, but not all, of the captive primate species. A human colonic methanogen, Methanobrevibacter smithii, was detected in all captive hominoid species, indicating high similarity of methanogenic microbiota among these …
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CNS Remyelination and the Gut Microbiota
… of the immune system depend on signals from the microbiota, and we know that a well-coordinated immune response is a key determinant of the success of remyelination. This thesis explores how the microbiome can influence CNS remyelination. To do so, I have studied remyelination in three murine …
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Gut Microbiota Regulation of SLE Pathogenesis
… the intricate connection between SLE and the gut microbiota. A literature review offered a comprehensive analysis of current research, with a particular emphasis on potential interactions between bacterial flagellin and Toll-Like Receptor 5 (TLR5) on immune cells. These interactions garnered …
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Understanding the development of gut microbiota and effect of Salmonella Typhimurium infection on gut microbiota in layers
In the last two decades, the focus on chicken gut microbiota has increased exponentially due to its critical role in digestion, nutrient absorption, modulation of immunity, and protection against enteric pathogens. Thus, understanding its role in food-producing animals like chickens is essential …
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Interaction of skin cells with skin microbiota
The interaction between skin cells and skin microbiota is complicated and not fully understood. A diverse community of microbes resides on the skin that participates in shaping its physiology. Skin microbiota can modulate skin immunity and barrier, thus, contributing to skin health. Also, the …
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Gut Microbiota of Migratory Passerines at Stopover
<p>Although the gut microbiota provides many beneficial functions to animal hosts, relatively little is known about the gut microbiota of passerines. It is likely that gut microbes are especially important during the migratory phase; however gut atrophy experienced during prolonged migratory flight …
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The gut microbiota in immune-mediated disorders
The human gut microbiota is a diverse community of microbes residing in the intestine. Evidence from various animal models and human studies have highlighted its potential role in health, metabolic and immune-associated conditions such as osteoporosis, inflammatory arthritis, inflammatory bowel …
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Establishment and development of infant gut microbiota
The nascent gut microbiota at birth is established in concert with numerous developmental parameters. Here, in the INFAMTET study, we chronicled the impact of some factors which are key determinants of the infant gut microbiota, namely; mode of birth, gestational age, and type of feeding. We …
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Intestinal Inflammatory Responses to the Indigenous Microbiota
The potential for inflammatory cytokines to sensitize intestinal epithelial cells to indigenous bacteria was evaluated in HT-29 cells associated with Lactobacillus plantarum 299v in the presence or absence of tumor necrosis factor-alpha (TNF-alpha). Co-culture of TNF-alpha-stimulated HT-29 cells …
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Habitual gardening and the human gut microbiota
The student, Marina Brown, submitted this Thesis for approval on 2021-07-20 at 14:08.
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