Virginia Tech
Selection for serum cholesterol, voluntary physical activity, 56- day body weight and feed intake in albino mice
Abstract
dc:description.abstractA short-term selection experiment was conducted with ICR albino mice produced by the reciprocal crossing of two lines of unselected animals which had been random-bred for 28 generations. Lines were developed by selecting for maximum and minimum serum cholesterol (SC) (lines CH and CL), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL) and feed intake (lines IH and IL). An unselected, random-bred control line was maintained with each pair of divergent selected lines (CC, AC, NC and IC, respectively). In the lines selected for SC, physical activity and 56-day body weight, selection was based on individual performance. Twenty-five paired matings plus five extra paired matings were used to perpetuate the lines each generation for five generations. The feed intake lines were perpetuated by within-sex, full-sib family selection with 30 paired matings per generation for five generations.
Degree
thesis:*- Name thesis:degree_name
- Ph. D.
- Level thesis:degree_level
- doctoral
- Discipline thesis:degree_discipline
- Genetics
- Department dc:contributor.department
- Genetics
- Grantor dc:publisher
- Virginia Tech
- Year dc:date.issued
- 1978
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Dunnington, E. Ann
- Chair dc:contributor.committeechair
-
- White, John M.
- Committee members dc:contributor.committeemember
-
- Vinson, William E.
- Siegel, Paul B.
- Hinkelmann, Klaus H.
- Thye, Forrest W.
Rights
dc:rights- Statement dc:rights
-
- In Copyright
- Licence dc:rights.uri
- Language dc:language.iso
- en
Identifiers
dc:identifier.*- Dc Identifier Other
- etd-11292012-040248
- OAI identifier oai:identifier
- oai:vtechworks.lib.vt.edu:10919/40368