{"id":{"repo_id":"vt","oai_identifier":"oai:vtechworks.lib.vt.edu:10919/40368"},"canonical_url":"https://search.dev.ndltd.org/etd/vt/oai:vtechworks.lib.vt.edu:10919/40368","repository":{"repo_id":"vt","name":"Virginia Tech","base_url":"https://vtechworks.lib.vt.edu/oai/request"},"display":{"title":"Selection for serum cholesterol, voluntary physical activity, 56- day body weight and feed intake in albino mice","abstract":"A short-term selection experiment was conducted with ICR albino mice produced by the reciprocal crossing of two lines of unselected animals which had been random-bred for 28 generations. Lines were developed by selecting for maximum and minimum serum cholesterol (SC) (lines CH and CL), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL) and feed intake (lines IH and IL). An unselected, random-bred control line was maintained with each pair of divergent selected lines (CC, AC, NC and IC, respectively). In the lines selected for SC, physical activity and 56-day body weight, selection was based on individual performance. Twenty-five paired matings plus five extra paired matings were used to perpetuate the lines each generation for five generations. The feed intake lines were perpetuated by within-sex, full-sib family selection with 30 paired matings per generation for five generations.","abstract_html":"A short-term selection experiment was conducted with ICR albino mice produced by the reciprocal crossing of two lines of unselected animals which had been random-bred for 28 generations. Lines were developed by selecting for maximum and minimum serum cholesterol (SC) (lines CH and CL), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL) and feed intake (lines IH and IL). An unselected, random-bred control line was maintained with each pair of divergent selected lines (CC, AC, NC and IC, respectively). In the lines selected for SC, physical activity and 56-day body weight, selection was based on individual performance. Twenty-five paired matings plus five extra paired matings were used to perpetuate the lines each generation for five generations. The feed intake lines were perpetuated by within-sex, full-sib family selection with 30 paired matings per generation for five generations.","abstract_has_math":false,"creators":["Dunnington, E. Ann"],"institution":"Virginia Tech","degree_name":"Ph. D.","degree_level":"doctoral","degree_discipline":"Genetics","degree_department":"Genetics","school":null,"contributors":[],"advisors":[],"committee_chairs":["White, John M."],"committee_members":["Vinson, William E.","Siegel, Paul B.","Hinkelmann, Klaus H.","Thye, Forrest W."],"year":1978,"date_issued":"1978-01-15","date_published":"1978-01-15","updated_at":"2026-07-22T22:20:12Z","subjects":[],"languages":["en"],"rights":["In Copyright"],"rights_urls":["http://rightsstatements.org/vocab/InC/1.0/"],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["etd-11292012-040248"],"render_values":[{"text":"etd-11292012-040248","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10919/40368","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.committeechair","label":"Committee Chair","values":["White, John M."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Vinson, William E.","Siegel, Paul B.","Hinkelmann, Klaus H.","Thye, Forrest W."]},{"key":"dc:contributor.department","label":"Department","values":["Genetics"]},{"key":"dc:creator","label":"Author","values":["Dunnington, E. 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