Ankstyvosios diagnostikos programos poveikio sergamumui priešinės liaukos vėžiu Lietuvoje vertinimas /

Prostate cancer is most common and second deadliest tumour diagnosed in Lithuanian men. Prostate specific antigen (PSA) test in early detection of prostate cancer could result in decreased morbidity and mortality. Radical treatment of low-risk prostate emerged as an inevitable satellite of early detection. It is unknown if PSA testing offered to informed men by general practitioners (GP) could have the same results as in clinical trials. This study is the first evaluation of the nation wide prostate cancer detection program based on PSA testing. GP based early detection program is analysed according to the penetration of PSA testing in different age groups and the potential to decrease prostate cancer morbidity. The created database integrating data of PSA testing and incidence of prostate cancer permits in analysis of the effectiveness of early detection. Penetration of PSA testing was determined to be the lowest in 50-54 years men. After two years GP based PSA testing service resulted in decreased incidence of localized and locally advanced prostate cancer across 50-75 years men group. Results of the study suggest that men younger than 60 years need to be involved in early detection program by additional means of information. The active surveillance should be widely used for management of the low-risk prostate cancer.

Grantor dc:publisher

Institutional Repository of Vilnius University

Year dc:date

2012

Author dc:creator

• Adomaitis, Robertas,

Contributors dc:contributor

• Jankevičius, Feliksas

• prostate cancer ; PSA ; early detection

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

lit

Repository record dc:identifier

https://repository.vu.lt/VU:ELABAETD1995027&prefLang=en_US

OAI identifier oai:identifier

oai:vu.lt:elaba:1995027