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Showing 1 to 20 of 55 for “"Prostate specific antigen"”.
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Relationship between abdominal obesity and Prostate specific antigen level
본 연구는 남성의 전립샘특이항원수치에 영향을 미치는 요인에 관한 위한 연구이며, 비만 중에서도 복부비만에 초점을 두었다. 구체적인 연구문제는 다음과 같다. 첫째, 조사대상자의 특성과 비만정도에 따라 전립샘특이항원 수치에 차이가 잇는지 파악한다. 둘째, 조사대상자의 복부비만이 전립샘특이항원 수치에 미치는 영향을 파악한다. 자료는 수원시 소재 대학병원 종합검진 남성 수검자들을 대상으로 검사결과와 의무기록을 통해 수집하였고 1039명의 데이터를 분석하였다. 사용된 통계기법은 빈도분석, 기술통계, 독립표본 t검정, 일원배치분산분석, …
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Prostate-specific Antigen Nadir and Time to Prostate-specific Antigen Nadir Following Maximal Androgen Blockade Independently Predict the Prognosis in Patients with Metastatic Prostate Cancer
PURPOSE: To evaluate the influence of prostate-specific antigen (PSA) kinetics following maximal androgen blockade (MAB) on the disease progression and cancer-specific survival in patients with metastatic, hormone sensitive prostate cancer. MATERIALS AND METHODS: One hundred thirty-one patients …
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Fluorescence resonance energy transfer-based biosensors for monitoring prostate specific antigen
Prostate cancer has become the most commonly diagnosed cancer in men in the United States. Clinical diagnostic procedures currently include prostate-specific antigen (PSA) screening, digital rectal exam, and prostatic needle biopsy. However, these methods lack the sensitivity to detect small …
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Prostate Specific Antigen Screening in Texas Medicare Population: The Role of Patient Characteristics
… study were to 1) determine the prevalence of prostate specific antigen (PSA) testing in the Texas Medicare population and 2) assess which patient characteristics are associated with receipt of PSA screening. The 100% Texas Medicare claims data and 2009 population estimates from the Dartmouth …
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Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids
<p>Presently, prostate cancer is the most common cancer afflicting men in the United States, with serum PSA being the "gold standard" protein biomarker used in the clinic for detecting and diagnosing prostate cancer. Nonetheless, serum PSA levels can also be elevated in non-cancerous conditions as …
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Hospitalization Itself Decreases the Serum Prostate-specific Antigen Values Compared to the Outpatient Values in Patients with Benign Prostatic Diseases
… AND METHODS: Transrectal ultrasound-guided prostate biopsies were performed for detecting prostate cancer in 2,017 patients between February 2001 and April 2011 at our institution. Among them, 416 patients who were hospitalized for prostate biopsies, whose serum PSA values were checked at …
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Design, Synthesis, and Screening of Novel Phosphatidylinositol 3-Kinase (PI3K) Inhibitors Activated by Prostate Specific Antigen (PSA): Prodrug Treatment for Androgen-Independent Prostate Cancer
… drugs are potent, but often lack the cellular specificity needed to lower toxicity effects. Here we show the design and synthesis of two types of novel PSA-activated PI3K inhibitors for the treatment of androgen-independent prostate cancer. Both literature and predictive molecular modeling …
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Evaluation of a stage II screening protocol for prostate cancer
In 2003, prostate cancer (PCa) is estimated to be the most commonly diagnosed cancer and third leading cause of cancer death in Canada. During PCa population screening, approximately 25% of patients with a normal digital rectal examination (DRE) and intermediate serum prostate specific antigen …
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SYNTHESIS AND SCREENING OF PI3K INHIBITOR PRODRUGS FOR TREATMENT OF PROSTATE CANCER
Prostate cancer is the most common non-skin cancer in American men. At the current time, there is no effective treatment for men with metastatic prostate cancer. Androgen ablation is the most successful systemic treatment for prostate cancer. However, the cancer eventually recurs as …
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ΔΙΕΡΕΥΝΗΣΗ ΤΟΥ ΡΟΛΟΥ ΤΟΥ ΕΙΔΙΚΟΥ ΠΡΟΣΤΑΤΙΚΟΥ ΑΝΤΙΓΟΝΟΥ (PSA) ΣΤΗΝ ΠΑΘΟΛΟΓΙΑ ΤΟΥ ΠΡΟΣΤΑΤΗ
WE MEASURED SERUM PROSTATE SPECIFIC ANTIGEN (PSA) FROM 135 MEN (55 PROSTATE CANCER, 39 BENIGN PROSTATE HYPERTROPHY, 9 PROSTATITIS, 32 NORMAL). PSA IS A SPECIFIC-CELL TYPE ANTIGEN OF PROSTATE AND IS MORE SENSITIVE MARKER THAN PROSTATE ACID PHOSPHATASE (PAP)-71% TO 27,3%. PSA CAN NOT SOLVE THE …
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Integrative Bioinformatics Approaches to Elucidating Prostate Cancer Cell Heterogeneity, Plasticity, and Treatment Response
<p>Prostate cancer (PCa) is the most common non-cutaneous tumor in American men, and the second leading cause of cancer-related deaths. PCa-related deaths can be attributed to heterogeneous tumors containing metastatic and therapy-resistant cancer cells. Cancer stem cells (CSC) are an important …
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Ankstyvosios diagnostikos programos poveikio sergamumui priešinės liaukos vėžiu Lietuvoje vertinimas /
Prostate cancer is most common and second deadliest tumour diagnosed in Lithuanian men. Prostate specific antigen (PSA) test in early detection of prostate cancer could result in decreased morbidity and mortality. Radical treatment of low-risk prostate emerged as an inevitable satellite of early …
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An MRI compatible manipulator for prostate cancer detection and treatment
Prostate cancer is the most frequently diagnosed cancer in men and the second most common cause of cancer related death in men. Prostate specific antigen (PSA) blood tests and digital rectal exams (DRE) are preliminary tests that can suggest the presence of prostate cancer. Following these tests, a …
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Nanomaterials for the detection of cancer-associated biomarkers
Prostate cancer persists as a major public health issue in the United States and remains the second leading cause of cancer death in men. Early detection and disease monitoring in prostate cancer can significantly improve a patient's prognosis. The advent of prostate-specific antigen (PSA) …
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Antibody-based biosensor assays for the detection of zilpaterol and markers for prostate cancer
… and the application of antibodies against prostate-specific antigen (PSA), a cancer marker. Polyclonal antibodies were used in the development of immunoassays in a competitive ELISA format and on the Biacore (a surface plasmon resonance-based optical biosensor capable of monitoring …
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Investigation of the anti-cancer effects of rosemary (Rosmarinus Officinalis L.) extract in human breast and prostate cancer cells
Breast and prostate cancer are the most frequently diagnosed cancers in women and men respetively, in North America. Triple-negative breast cancer (TNBC) cells do not express estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 (HER-2). TNBC accounts for 15% of all …
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Effect of a novel contraceptive compound on vaginal health
… triazole B1. B1 acts to block the activity of prostate specific antigen, the serine protease responsible for initiating the liquefaction process by cleaving the protein SEMG-1. B1 is intended to be used as a local vaginal gel contraceptive and not as a systemic drug. Therefore, we need to …
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Antimicrobial activity of human seminal plasma and seminal plasma proteins
… glands, mainly the seminal vesicles and the prostate. Seminal plasma has high protein content and it also contains ions, sugars and low molecular weight components. Immediately after ejaculation the semenogelins and fibronectin aggregate and a coagulum forms trapping the spermatozoa. Seminal …
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Characterizing glucocorticoid receptor in metastatic castration resistant prostate cancer
… in the context of enzalutamide resistant prostate cancer cells. Enzalutamide is a drug that functions to dampen androgen receptor (AR) signaling, thus inhibiting cancer dependency on the receptor protein. Although the application of the drug reduces AR signaling in these cancer cells, an …
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Risk Factors for Acute Prostatitis after Transrectal Biopsy of the Prostate
… with acute prostatitis after transrectal prostate biopsy. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 923 transrectal ultrasound-guided needle biopsy of the prostate on 878 patients performed in our institution from June 2004 to May 2009. The indications for …
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