Components of Oral Health in End-stage Chronic Kidney Disease Patients Undergoing Chronic Dialysis Treatment /// Компоненти на орално здраве при пациенти в терминален стадий на хронично бъбречно заболяване на хрониодиализно лечение

[EN] Chronic kidney disease (CKD) represents a global health issue with a rising prevalence - a clinical-laboratory syndrome, occurring as a result of progressive loss of renal function and failure for months or years. Due to the underlying disease and long dialysis treatment, end-stage CKD patients are at a higher risk of developing typical oral manifestations. The aim of the dissertation was to research the manifestation, prevalence and type of oral health components in end-stage CKD patients, undergoing renal replacement therapy. Drawing upon latest clinical and laboratory methods, the study also aimed at developing a protocol for diagnosis and evaluation of the clinical condition of CKD patients that could be applied in clinical practices. The study targeted 70 patients diagnosed with end-stage CKD patients on haemodialysis treatment of different duration. A Diagnostic Card was designed to record patients’ medical history taken, oral status, gingival condition (PBI index), oral hygiene (Greene and Vermillion index), tongue coating and halitosis condition. Laboratory methods were applied to determine urea, creatinine, calcium and inorganic phosphorus levels in blood serum and in whole unstimulated saliva. Quantification of sIgA levels from salivary medium was performed using radial immunodiffusion (Mancini method). The protocol for diagnosis and evaluation of oral health was based on statistical analysis and the reliable test results obtained.

Authors dc:creator

• Nenova-Nogalcheva, Anna
• Ненова-Ногалчева, Анна

• oral health
• chronic kidney disease (CKD)
• end-stage CKD
• hemodialysis
• Орална и лицево-челюстна хирургия / Oral and Maxillofacial Surgery

Repository record dc:identifier

http://repository.mu-varna.bg/handle/nls/415

OAI identifier oai:identifier

oai:repository.mu-varna.bg:nls/415