Acute Coronary Syndrome in Patients with Chronic Obstructive Pulmonary Disease // Остър коронарен синдром при пациенти с хронична обструктивна белодробна болест

The thesis presents the first scientific study on the risk, clinical characteristics, and adherence to prescribed drug therapy in patients with acute coronary syndrome (ACS) and chronic obstructive pulmonary disease (COPD) in Northeast Bulgaria. The clinical appearance and therapeutic behaviour of individuals with ACS and concomitant COPD compared to a control group with no data on pulmonary obstruction were examined. The reasons for rehospitalisation, as well as the quality of life in both groups of patients, were investigated. The clinical and demographic characteristics of the deceased patients were analysed. Patients with ACS and COPD had a more prominent risk profile for ICD than patients with ACS and no COPD, according to the comparison analysis between the two study groups. Up to 12 months following the acute coronary event, people with pulmonary obstruction had an increased likelihood of being admitted to the hospital for cardiovascular disease. The most frequent cause was CHF, which was followed by ICD. In this patient sample, higher baseline CRP values, smoking, a higher BMI, and less physical exercise have been associated with higher mortality. The following scientific data demonstrates that people with ACS and COPD are a high-risk population that needs additional research and monitoring. Creating an exceptional algorithm is just one step towards improving the treatment these patients get.

Grantor dc:publisher

Medical University of Varna

Year dc:date

2025

Authors dc:creator

• Yankova, Simona
• Янкова, Симона

• acute coronary syndrome
• COPD
• pulmonary obstruction
• cardiovascular disease
• Кардиология / Cardiology

Repository record dc:identifier

http://repository.mu-varna.bg/handle/nls/4107

OAI identifier oai:identifier

oai:repository.mu-varna.bg:nls/4107