Molecular Underpinnings of Human Brain Evolution and Cognition at Cellular Resolution

The second part of Chapter 1 is modified from a commissioned book chapter (accepted for publication) titled "Differences in brain gene expression between humans and primates", which has been accepted for publication as a chapter in the book titled "The evolutionary roots of human brain diseases". This chapter is an edited version of the author's own original writing with additional edits by the author's thesis supervisor and from feedback from the editors of the book. The citation to the book is included below.

Author dc:creator

• Caglayan, Emre

Contributors dc:contributor

• Chahrour, Maria
• Hon, Gary C.
• Madabhushi, Ram
• Sun, Lu O.
• Konopka, Genevieve

• Autism Spectrum Disorder
• Cell Nucleus
• Evolution, Molecular
• Gyrus Cinguli
• Memory, Episodic
• RNA
• Temporal Lobe
• Transcriptome

Language dc:language

en

Identifier

Konopka, G., & Caglayan, E. (2024). Differences in brain gene expression between humans and primates. In N. J. Diederich, M. Brüne, K. Amunts, & C. G. Goetz (Eds.), The evolutionary roots of human brain diseases. Oxford University Press.
Caglayan, E., Ayhan, F., Liu, Y., Vollmer, R. M., Oh, E., Sherwood, C. C., Preuss, T. M., Yi, S. V., & Konopka, G. (2023). Molecular features driving cellular complexity of human brain evolution. Nature, 620(7972), 145-153. https://doi.org/10.1038/s41586-023-06338-4
Caglayan, E., Liu, Y., & Konopka, G. (2022). Neuronal ambient RNA contamination causes misinterpreted and masked cell types in brain single-nuclei datasets. Neuron, 110(24), 4043-4056 e4045. https://doi.org/10.1016/j.neuron.2022.09.010
Berto, S., Treacher, A. H., Caglayan, E., Luo, D., Haney, J. R., Gandal, M. J., Geschwind, D. H., Montillo, A. A., & Konopka, G. (2022). Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nat Commun, 13(1), 3328. https://doi.org/10.1038/s41467-022-31053-5
Berto, S., Fontenot, M. R., Seger, S., Ayhan, F., Caglayan, E., Kulkarni, A., Douglas, C., Tamminga, C. A., Lega, B. C., & Konopka, G. (2021). Gene-expression correlates of the oscillatory signatures supporting human episodic memory encoding. Nat Neurosci, 24(4), 554-564. https://doi.org/10.1038/s41593-021-00803-x
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OAI identifier oai:identifier

oai:utswmed-ir.tdl.org:2152.5/10239