Odor sensitivity and the presence of p-cresol

Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients.

Grantor dc:publisher

University of Tennessee at Chattanooga

Author dc:creator

• McKinney, Jessica Mi

Contributors dc:contributor

• Ozbek, Irene Nichols, 1947-
• Warren, Amye; Whitson, Stefanie R.
• College of Arts and Sciences

• Smell -- Threshold
• Odors -- Psychological aspects

Licence

• https://rightsstatements.org/page/InC/1.0/?language=en

Language dc:language

English, eng

Repository record dc:identifier

https://scholar.utc.edu/theses/338

OAI identifier oai:identifier

oai:scholar.utc.edu:theses-1478