{"id":{"repo_id":"utc","oai_identifier":"oai:scholar.utc.edu:theses-1478"},"canonical_url":"https://search.dev.ndltd.org/etd/utc/oai:scholar.utc.edu:theses-1478","repository":{"repo_id":"utc","name":"University of Tennessee - Chattanooga","base_url":"https://scholar.utc.edu/do/oai/"},"display":{"title":"Odor sensitivity and the presence of p-cresol","abstract":"Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients.","abstract_html":"Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients.","abstract_has_math":false,"creators":["McKinney, Jessica Mi"],"institution":"University of Tennessee at Chattanooga","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Ozbek, Irene Nichols, 1947-","Warren, Amye; Whitson, Stefanie R.","College of Arts and Sciences"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":null,"date_issued":"","date_published":null,"updated_at":"2026-07-24T05:46:19Z","subjects":["Smell -- Threshold","Odors -- Psychological aspects"],"languages":["English","eng"],"rights":[],"rights_urls":["https://rightsstatements.org/page/InC/1.0/?language=en"],"identifier_entries":[]},"links":{"outbound_url":"https://scholar.utc.edu/theses/338","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Ozbek, Irene Nichols, 1947-","Warren, Amye; Whitson, Stefanie R.","College of Arts and Sciences"]},{"key":"dc:creator","label":"Author","values":["McKinney, Jessica Mi"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2013-05-01T07:00:00Z"]},{"key":"dc:publisher","label":"Institution","values":["University of Tennessee at Chattanooga","Chattanooga (Tenn.)"]},{"key":"dc:relation","label":"Dc Relation","values":["Masters Theses and Doctoral Dissertations"]},{"key":"dc:type","label":"Dc Type","values":["Masters theses","Text"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Smell -- Threshold","Odors -- Psychological aspects"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["https://rightsstatements.org/page/InC/1.0/?language=en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholar.utc.edu/theses/338"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Dept. of Psychology","M. S.; A thesis submitted to the faculty of the University of Tennessee at Chattanooga in partial fulfillment of the requirements of the degree of Master of Science."]},{"key":"dc:description.abstract","label":"Abstract","values":["Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients."]},{"key":"dc:title","label":"Title","values":["Odor sensitivity and the presence of p-cresol"]}]}],"canonical_facts":{"dc:contributor":["Ozbek, Irene Nichols, 1947-","Warren, Amye; Whitson, Stefanie R.","College of Arts and Sciences"],"dc:creator":["McKinney, Jessica Mi"],"dc:date":["2013-05-01T07:00:00Z"],"dc:description":["Dept. of Psychology","M. S.; A thesis submitted to the faculty of the University of Tennessee at Chattanooga in partial fulfillment of the requirements of the degree of Master of Science."],"dc:description.abstract":["Olfactory function declines throughout the different stages of kidney disease. End-stage renal disease (ESRD) patients have experienced improved olfactory function after dialysis, leading some researchers to suspect uremic toxins as the cause of olfactory decline (Raff et al., 2008; Bomback & Raff, 2011). It is thought that p-cresol is the specific uremic toxin to cause a decline in olfactory function because it is not easily filtered out of the blood during dialysis (Meijers et al., 2010). The study sought to set up a control group for future studies by demonstrating p-cresol is not in the blood of healthy participants and to collect normative values for an olfactory threshold test. Results supported the hypothesis that p-cresol is not present in the blood of healthy participants, which strengthens the idea that p-cresol may be the cause of olfactory dysfunction in ESRD patients."],"dc:identifier":["https://scholar.utc.edu/theses/338"],"dc:language":["English","eng"],"dc:publisher":["University of Tennessee at Chattanooga","Chattanooga (Tenn.)"],"dc:relation":["Masters Theses and Doctoral Dissertations"],"dc:rights":["https://rightsstatements.org/page/InC/1.0/?language=en"],"dc:subject":["Smell -- Threshold","Odors -- Psychological aspects"],"dc:title":["Odor sensitivity and the presence of p-cresol"],"dc:type":["Masters theses","Text"]},"updated_at":"2026-07-24T05:46:19Z"}