6,6’-Dimethoxygossypol: Molecular Structure, Crystal Polymorphism, and Solvate Formation.

<p>6,6’-Dimethoxygossypol (DMG) is a natural product of the cotton variety Gossypium barbadense and a derivative of gossypol. Gossypol has been shown to form an abundant number of clathrates with a large variety of compounds. One of the primary reasons why gossypol can form clathrates has been because of its ability to from extensive hydrogen bonding networks due to its hydroxyl and aldehyde functional groups. Prior to this work, the only known solvate that DMG formed was with acetic acid. DMG has methoxy groups substituted at two hydroxyl positions, and consequently there is a decrease in its ability to form hydrogen bonds. Crystallization experiments were set up to see whether, like gossypol, DMG could form clathrates. The following results presented prove that DMG is capable of forming clathrates (S1 and S2) and two new polymorphs (P1 and P2) of DMG have been reported.</p>

Name thesis:degree_name

M.S.

Level thesis:degree_level

Thesis-Restricted

Discipline thesis:degree_discipline

Chemistry

Year

2011

Author dc:creator

• Zelaya, Carlos A.

Contributors dc:contributor

• Steven, Edwin D.
• Dowd, Michael K.
• Mobley, David L.

• Gossypol
• x-ray crystallography
• clathrates
• solvates
• hydrogen bonding
• functional groups
• polymorphs
• and space groups

Repository record dc:identifier

https://scholarworks.uno.edu/td/136

OAI identifier oai:identifier

oai:scholarworks.uno.edu:td-1135