Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics

Embargo set by: Seth Robbins for item 91378 Lift date: 2018-03-02T20:57:40Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2016

Author dc:creator

• Parkinson, Elizabeth Ivy

Contributors dc:contributor

• Hergenrother, Paul J.
• Burke, Martin D.
• van der Donk, Wilfred A.
• Mitchell, Douglas A.

• NAD(P)H:quinone oxidoreductase-1 (NQO1)
• reduction-oxidation cycling
• deoxynyboquinone
• anticancer
• fluoroquinolones
• antibiotic resistance
• deoxynybomycin
• DNA gyrase

Statement dc:rights

• Copyright 2015 Elizabeth Parkinson

Language dc:language

en

Handle dc:identifier

http://hdl.handle.net/2142/89176

OAI record oai:identifier

https://www.ideals.illinois.edu/oai-pmh?verb=GetRecord&metadataPrefix=etdms&identifier=oai%3Awww.ideals.illinois.edu%3A2142%2F89176