Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics

Made available in DSpace on 2016-03-02T20:57:24Z (GMT). No. of bitstreams: 5 PARKINSON-DISSERTATION-2015.pdf: 21604741 bytes, checksum: 36ce90169c82a68c9b09739d5545d439 (MD5) LICENSE.txt: 4216 bytes, checksum: 30a9874759f4e96d3a10d148120d7757 (MD5) Parkinson Supplemental 1.pdf: 124148 bytes, checksum: a4576e5e60bec59bccf8c405e2d7b706 (MD5) Parkinson Supplemental 2.pdf: 108772 bytes, checksum: 4e6a52d12f29118028d455b7ce5e7748 (MD5) Parkinson Supplemental 3.pdf: 532033 bytes, checksum: 3abecad33d597e0d1d5234b3ba75ea78 (MD5) Previous issue date: 2015-09-23

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2016

Author dc:creator

• Parkinson, Elizabeth Ivy

Contributors dc:contributor

• Hergenrother, Paul J.
• Burke, Martin D.
• van der Donk, Wilfred A.
• Mitchell, Douglas A.

• NAD(P)H:quinone oxidoreductase-1 (NQO1)
• reduction-oxidation cycling
• deoxynyboquinone
• anticancer
• fluoroquinolones
• antibiotic resistance
• deoxynybomycin
• DNA gyrase

Statement dc:rights

• Copyright 2015 Elizabeth Parkinson

Language dc:language

en

Handle dc:identifier

http://hdl.handle.net/2142/89176

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/89176