An Analysis of the Efficacy of Cervical Cancer Screening in Elderly Women

Recent studies have failed to reach a consensus on whether Papanicolaou (Pap) smear screening tests should be administered to women aged 65 years and older. Our case-control study utilized 2,778 incident cervical cancer cases from the Surveillance, Epidemiology and End Results (SEER) program registries that were diagnosed between 1991 and 1999. Population controls (N=10,137) were matched on age and geographical location to cases and were identified through a random 5% sample of Medicare beneficiaries living in regions of the United States covered by the SEER program registries. Pap smear screening history information for cases and controls was ascertained from Medicare billing records. Estimates of population hysterectomy prevalence from the National Health Interview Survey (NHIS) were used to obtain a hysterectomy-adjusted estimate of screening efficacy, controlled for race and education (OR = 0.39, CI = 0.33-0.44). Further analyses illustrated that cervical cancer screening had a negative association for women of all age groups, including women aged 65-75 (OR = 0.23, CI = 0.14-0.34), women aged 75-85 (OR = 0.48, CI = 0.38-0.61) and women aged 85 and above (OR = 0.45, CI = 0.29-0.70). In addition, analyses stratified on cancer stage showed that the Pap smear cervical cancer screening had a stronger negative association.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Kinesiology and Community Health

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Maduram, David Thomas

Contributors dc:contributor

• Rosenblatt, Karin

• Gerontology

Language dc:language

eng

Identifier

(MiAaPQ)AAI3290308

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/86391