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University of Illinois at Urbana-Champaign

Engineering Enhanced Cytochromes P450: Understanding Thermostability and Mechanism Through Rational Design and Directed Evolution

Abstract

dc:description

Although random and rational approaches for protein engineering are often used as separate approaches, this work has demonstrated the benefits of combining these approaches. Through the use of both methods a better understanding of thermostability, catalytic mechanism and substrate specificity was gained.

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Biochemistry
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2015

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Maves, Shelley Ann
Contributors dc:contributor
  • Sligar, Stephen G.

Subjects

dc:subject × 1

Rights

Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
(MiAaPQ)AAI9996660
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/84922

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Maves, Shelley Ann. Engineering Enhanced Cytochromes P450: Understanding Thermostability and Mechanism Through Rational Design and Directed Evolution. Dissertation thesis, University of Illinois at Urbana-Champaign, 2015. http://hdl.handle.net/2142/84922