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University of Illinois at Urbana-Champaign
Probing the Roles of Metal Binding Ligands in Cupredoxins: Incorporating Nonproteinogenic Amino Acids Into Azurin and Copper a Azurin
Abstract
dc:descriptionIn summary, a means to investigate the specific function of individual metal ligand residues in azurin and CuA azurin by using EPL to incorporate nonproteinogenic amino acid analogues has been demonstrated. This work has resulted in new insights into the role of the metal ligands and has shaped future metalloprotein engineering efforts.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Biochemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Clark, Kevin M.
- Contributors dc:contributor
-
- Lu, Yi
- Wilfred Van Der Donk
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3452158
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84870