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University of Illinois at Urbana-Champaign
Characterization of Antigen Recognition by a T Lymphocyte Clone
Abstract
dc:descriptionChapter Four addresses the physiological T cell responses that can be elicited by peptide/MHC recognition. We demonstrated that the endogenously derived peptide, dEV8, functioned as both an agonist and an antagonist of T cells derived from 2C TCR transgenic mice. Although the exact mechanism underlying the opposing effects of the same pepMHC complex remains to be determined, differences in accessory molecules or coreceptors on the T cell surface may have a significant impact on T cell signaling and function.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Biochemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2002
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Lee, Peter, Uang-Yin
- Contributors dc:contributor
-
- Kranz, David M.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3102037
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84802