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University of Illinois at Urbana-Champaign
Synthetic Chiral Stationary Phases in Enantioselective Liquid Chromatography
Abstract
dc:descriptionThe occurrence of π - π face to face and π - π face to edge interactions on a particular type of chiral stationary phase (CSP) used for chromatographic separations of enantiomers has been studied. Highly polarizable aromatic substituents, such as halogens, have been found to enhance π - π face to face interactions and can be used in the designs of new CSPs so as to improve their enantioselectivity. The structural elements required for successful enantioseparations of hydantoins and thiohydantoins were systematically investigated with the aforementioned CSP. Additionally, a new CSP in its family was rationally designed and synthesized in an attempt to optimize its chromatographic performance.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Gan, Kevin Ze
- Contributors dc:contributor
-
- Pirkle, William H.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI9834677
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84397