Off-Line CE/MALDI MS: Sampling and Deposition Techniques to Incorporate Complementary Analyses for Cellular Assays

The viability of this CE/MS method is demonstrated by the chemical profiling of tissues and single cells from the marine mollusc, Aplysia californica , assaying neuronal release, analyzing cone snail venoms, and incorporating radionuclide detection with CE/MALDI MS. The application of the CE/MS technique toward the analysis of these samples shows that this method is capable of analyzing the neuropeptides in single neurons, and it is also amendable to a wide variety of other areas where there is need to get more information from mass-limited samples.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Page, Jason Steven

Contributors dc:contributor

• Sweedler, Jonathan V.

• Biology, Neuroscience

Language dc:language

eng

Identifier

(MiAaPQ)AAI3070406

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/84087